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A patient with Chronic Calcific Pancreatitis: the Task with Many Unknowns

https://doi.org/10.31550/1727-2378-2023-22-8-55-60

Abstract

Aim. To describe a clinical case of a patient with diabetes mellitus in the outcome of chronic calcific pancreatitis.
Key points. Chronic pancreatitis is a multifaceted disease complicating a great number of body systems work. Currently, the problem of post-pancreatitis diabetes mellitus is receiving more and more attention precisely because simultaneous decrease of the endo- and exocrine functions of the pancreas without timely correction is accompanied by concomitant metabolic disorders that lead to different complaints, hiding the underlying cause. In addition to the familiar to endocrinologists’ problem of correcting hyperglycemia, there is also the problem of exocrine pancreatic insufficiency and vitamin-mineral-protein deficiency. Our patient’s dysfunction of the pancreas was reflected in the appearance of secondary hyperparathyroidism with the formation of osteoporosis, decreased growth, and a pathological fracture. The presented clinical case demonstrates the variety and scale of complications that develop in a patient with chronic calculous pancreatitis.
Conclusion. Careful history taking and a comprehensive examination of a patient with a long story of chronic alcoholic pancreatitis should contribute to the timely diagnosis and correction of diseases that develop due to a progressive loss of endo- and exocrine pancreatic function.

About the Authors

A. S. Ametov
Russian Medical Academy of Continuous Professional Education
Russian Federation

2/1 Barrikadnaya Str., build. 1, Moscow, 125993



A. V. Shabunin
Russian Medical Academy of Continuous Professional Education; Botkin Hospital
Russian Federation

2/1 Barrikadnaya Str., build. 1, Moscow, 125993

52nd Botkinsky pr-d, Moscow, Russian Federation 125284



E. Yu. Pashkova
Russian Medical Academy of Continuous Professional Education; Botkin Hospital
Russian Federation

2/1 Barrikadnaya Str., build. 1, Moscow, 125993

52nd Botkinsky pr-d, Moscow, Russian Federation 125284



V. B. Rumer
Botkin Hospital
Russian Federation

52nd Botkinsky pr-d, Moscow, 125284



K. A. Amikishieva
Russian Medical Academy of Continuous Professional Education; Botkin Hospital
Russian Federation

2/1 Barrikadnaya Str., build. 1, Moscow, 125993

52nd Botkinsky pr-d, Moscow, Russian Federation 125284



D. M. Antsiferova
Russian Medical Academy of Continuous Professional Education; Endocrinology Dispensary at Moscow Healthcare Department
Russian Federation

2/1 Barrikadnaya Str., build. 1, Moscow, 125993

37 Prechistenka St., Moscow, 119034



References

1. Rickels M.R., Norris A.W., Hull R.L. A tale of two pancreases: exocrine pathology and endocrine dysfunction. Diabetologia. 2020;63(10):2030–9. DOI: 10.1007/s00125-020-05210-8

2. Bhattamisra S.K., Siang T.C., Rong C.Y., Annan N.C. et al. Type-3c diabetes mellitus, diabetes of exocrine pancreas — an update. Curr. Diabetes Rev. 2019;15(5):382–94. DOI: 10.2174/1573399815666190115145702

3. Wynne K., Devereaux B., Dornhorst A. Diabetes of the exocrine pancreas. J. Gastroenterol. Hepatol. 2019;34(2):346–54. DOI: 10.1111/jgh.14451

4. Petrov M.S., Yadav D. Global epidemiology and holistic prevention of pancreatitis. Nat. Rev. Gastroenterol. Hepatol. 2019;16(3):175–84. DOI: 10.1038/s41575-018-0087-5

5. Ewald N., Kaufmann C., Raspe A., Kloer H.U. et al. Prevalence of diabetes mellitus secondary to pancreatic diseases (type 3c). Diabetes Metab. Res. Rev. 2012;28(4):338–42. DOI: 10.1002/dmrr.2260

6. Woodmansey C., McGovern A.P., McCullough K.A., Whyte M.B. et al. Incidence, demographics, and clinical characteristics of diabetes of the exocrine pancreas (type 3c): a retrospective cohort study. Diabetes Care. 2017;40(11):1486–93. DOI: 10.2337/dc17-0542

7. Bedin V.V. Chronic pancreatitis and its complications. Individualized approach to diagnosis and surgical treatment: Doctoral Theses. M.; 2020 266 p. (in Russian)


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For citations:


Ametov A.S., Shabunin A.V., Pashkova E.Yu., Rumer V.B., Amikishieva K.A., Antsiferova D.M. A patient with Chronic Calcific Pancreatitis: the Task with Many Unknowns. Title. 2023;22(8):55-60. (In Russ.) https://doi.org/10.31550/1727-2378-2023-22-8-55-60

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ISSN 1727-2378 (Print)
ISSN 2713-2994 (Online)