A Hip Fracture in a Young Patient as a Manifestation of Primary Hyperparathyroidism
A. S. Ametov,
E. Yu. Pashkova,
B. M. Kalinsky,
T. V. Shevyakova,
A. I. Evsikov,
A. V. Bedina,
E. N. Vengerova,
V. E. Bairova https://doi.org/10.31550/1727-2378-2024-23-4-67-72
Abstract
Aim. To demonstrate the development of severe bone and visceral manifestations of primary hyperparathyroidism in a patient with a parathyroid adenoma, without complaints until the occurrence of a low-traumatic femoral neck fracture.
Key points. Fibrocystic osteitis is a severe disabling manifestation of primary hyperparathyroidism. Early diagnosis has certain difficulties due to the variability of clinical manifestations, the lack of calcium screening at the outpatient stage and the low alertness among doctors in related specialties regarding primary hyperparathyroidism.
Conclusion. Delayed diagnosis of primary hyperparathyroidism can lead to disability and a significant decrease in the quality of patients’ lives. Thus, it is extremely important to be alert to this disease, especially in young patients with signs of bilateral nephrocalcinosis, low-traumatic fractures. It is also vital to raise awareness about the primary hyperthyroidism among doctors specializing in adjacent fields.
About the Authors
A. S. Ametov
Botkin Hospital; Russian Medical Academy of Continuous Professional Education
Russian Federation
Russian Federation
Ametov, A.S.
5 2nd Botkinsky pr-d, Moscow, 125284
2/1 Barrikadnaya Str., build. 1, Moscow, 125993
E. Yu. Pashkova
Botkin Hospital; Russian Medical Academy of Continuous Professional Education
Russian Federation
Russian Federation
Pashkova, E.Yu.
5 2nd Botkinsky pr-d, Moscow, 125284
2/1 Barrikadnaya Str., build. 1, Moscow, 125993
B. M. Kalinsky
Botkin Hospital
Russian Federation
Russian Federation
Kalinsky, B.M.
5 2nd Botkinsky pr-d, Moscow, 125284
T. V. Shevyakova
Botkin Hospital
Russian Federation
Russian Federation
Shevyakova, T.V.
5 2nd Botkinsky pr-d, Moscow, 125284
A. I. Evsikov
Botkin Hospital
Russian Federation
Russian Federation
Evsikov, A.I.
5 2nd Botkinsky pr-d, Moscow, 125284
A. V. Bedina
I.M. Sechenov First Moscow State Medical University (Sechenov University)
Russian Federation
Russian Federation
Bedina, A.V.
8 Trubetskaya Str., build. 2, Moscow, 119048
E. N. Vengerova
Botkin Hospital
Russian Federation
Russian Federation
Vengerova, E.N.
5 2nd Botkinsky pr-d, Moscow, 125284
V. E. Bairova
Botkin Hospital
Russian Federation
Russian Federation
Bairova, V.E.
5 2nd Botkinsky pr-d, Moscow, 125284
References
1. Kowalski G.J., Buła G., Żądło D., Gawrychowska A. et al. Primary hyperparathyroidism. Endokrynol. Pol. 2020;71(3):260–70. DOI: 10.5603/EP.a2020.0028
2. Misiorowski W., Czajka-Oraniec I., Kochman M., Zgliczyński W. et al. Osteitis fibrosa cystica — a forgotten radiological feature of primary hyperparathyroidism. Endocrine. 2017;58(2):380–5. DOI: 10.1007/s12020-017-1414-2
3. Minisola S., Arnold A., Belaya Z., Brandi M.L. et al. Epidemiology, pathophysiology, and genetics of primary hyperparathyroidism. J. Bone Miner. Res. 2022;37(11):2315–29. doi: 10.1002/jbmr.4665
4. Bandeira F., Cusano N.E., Silva B.C., Cassibba S. et al. Bone disease in primary hyperparathyroidism. Arq. Bras. Endocrinol. Metabol. 2014;58(5):553–61. DOI: 10.1590/0004-2730000003381
5. Cherian E.T., Guttenberg K.B., Osteitis fibrosa cystica, QJM. Int. J. Med. 2018;111(7):487. DOI: 10.1093/qjmed/hcy019
6. Mokrysheva N.G., Mirnaya S.S., Dobreva E.A., Maganeva I.S. et al. Primary hyperparathyroidism in Russia according to the registry. Problems of Endocrinology. 2019;65(5):300–10. (in Russian). DOI: 10.14341/probl10126
Review
For citations:
Ametov A.S., Pashkova E.Yu., Kalinsky B.M., Shevyakova T.V., Evsikov A.I., Bedina A.V., Vengerova E.N., Bairova V.E. A Hip Fracture in a Young Patient as a Manifestation of Primary Hyperparathyroidism. Title. 2024;23(4):67-72. (In Russ.) https://doi.org/10.31550/1727-2378-2024-23-4-67-72
Views:
56
Email this article 