Controversial Issues in the Management of Patients with HELLP Syndrome
https://doi.org/10.31550/1727-2378-2024-23-2-55-59
Abstract
Aim. To demonstrate a clinical case of HELLP syndrome with renal damage that required the use of therapeutic plasma exchange and to review the literature data on the treatment of this condition.
Key points. A clinical case of HELLP syndrome with renal dysfunction in a 19-year-old first-pregnant woman is described. The rapid development of the disease in the postpartum period required differential diagnosis of HELLP-syndrome with other types of thrombotic microangiopathy. Therapeutic plasma exchange was used in treatment.
Conclusion. Differential diagnosis of HELLP-syndrome and obstetric thrombotic microangiopathy attracts the interest of obstetriciangynecologists. In patient G. the differential diagnosis was carried out in full, according to the current clinical recommendations. Thus, effective therapy of HELLP-syndrome is possible with simultaneous influence on all pathogenetic links — activation of inflammation processes, endothelial dysfunction and coagulopathy.
About the Authors
V. V. Ishkaraeva
Almazov National Medical Research Centre
Russian Federation
Russian Federation
2, Akkuratov Str., litera B, Saint Petersburg, 197341.
I. E. Zazerskaya
Almazov National Medical Research Centre
Russian Federation
Russian Federation
2, Akkuratov Str., litera B, Saint Petersburg, 197341.
N. A. Osipova
Almazov National Medical Research Centre
Russian Federation
Russian Federation
2, Akkuratov Str., litera B, Saint Petersburg, 197341.
A. V. Yakubov
Almazov National Medical Research Centre
Russian Federation
Russian Federation
2, Akkuratov Str., litera B, Saint Petersburg, 197341.
V. A. Markina
Almazov National Medical Research Centre
Russian Federation
Russian Federation
2, Akkuratov Str., litera B, Saint Petersburg, 197341.
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Review
For citations:
Ishkaraeva V.V., Zazerskaya I.E., Osipova N.A., Yakubov A.V., Markina V.A. Controversial Issues in the Management of Patients with HELLP Syndrome. Title. 2024;23(2):55-59. (In Russ.) https://doi.org/10.31550/1727-2378-2024-23-2-55-59
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