Gilbert’s Syndrome and Hemochromatosis in a Patient with Cytolysis and Hyperbilirubinemia
https://doi.org/10.31550/1727-2378-2024-23-1-73-76
Abstract
Aim. To present a clinical case of the combination of Gilbert's syndrome and primary hemochromatosis.
Key points. The article presents a clinical example demonstrating the complexity of diagnosing diseases caused by genetic polymorphism. Examination of the patient revealed impaired liver function, elevated levels of hemoglobin, serum iron, and transferrin saturation with iron, which led to suspicion of Gilbert's syndrome and primary hemochromatosis. These diagnoses were confirmed by genetic testing.
Conclusion. Diagnosis of the causes of liver damage requires first and foremost exclusion of the most likely ones, but it is important to keep in mind the possibility of continuing the search for the causes of the disease using specific diagnostic methods.
About the Authors
E. S. Bodryagina
Kazan State Medical University
Russian Federation
Russian Federation
49 Butlerov Str., Kazan, 420012
D. R. Akberova
Kazan State Medical University
Russian Federation
Russian Federation
49 Butlerov Str., Kazan, 420012
A. M. Nigmatullina
Kazan State Medical University
Russian Federation
Russian Federation
49 Butlerov Str., Kazan, 420012
U. F. Iskanderzade
Kazan State Medical University
Russian Federation
Russian Federation
49 Butlerov Str., Kazan, 420012
D. I. Gabelko
Kazan Federal University
Russian Federation
Russian Federation
2 N. Ershov Str., Kazan, 420061
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Review
For citations:
Bodryagina E.S., Akberova D.R., Nigmatullina A.M., Iskanderzade U.F., Gabelko D.I. Gilbert’s Syndrome and Hemochromatosis in a Patient with Cytolysis and Hyperbilirubinemia. Title. 2024;23(1):73-76. (In Russ.) https://doi.org/10.31550/1727-2378-2024-23-1-73-76
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