Role of Placentometry in Prediction of Early Preeclampsia
https://doi.org/10.31550/1727-2378-2022-21-1-13-17
Abstract
Study Objective: To identify predictors of early preeclampsia (PE) according to placentometry results, when an ultrasound screening is performed at week 19–21 of pregnancy in women with low risk of PE.
Study Design: Case–control study (paired comparison method).
Materials and Methods. The study enrolled 80 pregnant women. The study group included 40 patients with early PE, delivery time: week 28–32 of pregnancy. Controls were 40 women who delivered term infants without any signs of hypotrophy. We analysed ultrasound findings at week 19–21 of pregnancy in order to calculate the placental ratio score (PRi).
Study Results. Median PRi in controls was 6.68, i.e., significantly lower than in the study group (7.65 (р < 0.0001)). We calculated the threshold value of PRi which allows forecasting early PE in the low-risk group: PRi of ≥ 7 makes it possible to forecast early PE in 91.3% of cases, with the sensitivity of 90% and specificity of 87.5%.
Conclusion. Placentometry at week 19–21 of pregnancy with PRi calculation, where the length (diameter) of placenta is 120–167 mm, allows forecasting early PE in low-risk patients and timely stratifying pregnant women for additional examinations and preventive measures.
About the Authors
K. V. Schekleina
Altai State Medical University (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health ; DAR, Altai Territorial Perinatal Clinical Center (a Territorial Government-funded Healthcare Institution)
Russian Federation
Russian Federation
40 Lenin Prospect, Barnaul, 656038
154 Fomin St., Barnaul, 656048
M. G. Nikolaeva
Altai State Medical University (a Federal Government-funded Educational Institution of Higher Education), Russian Federation Ministry of Health ; Altay Branch of the National Medical Research Centre of Haematology of the Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
40 Lenin Prospect, Barnaul, 656038
51 Malakhov Str., Barnaul, 656050
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Review
For citations:
Schekleina K.V., Nikolaeva M.G. Role of Placentometry in Prediction of Early Preeclampsia. Title. 2022;21(1):13-17. (In Russ.) https://doi.org/10.31550/1727-2378-2022-21-1-13-17
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