Predictors of Recurrent Wheezing in Young Children
https://doi.org/10.31550/1727-2378-2024-23-6-88-92
Abstract
Aim. To provide overview information on predictors of relapses of bronchial obstruction in young children and the likelihood of them developing bronchial asthma in the future.
Key points. Over the past few years, more than 280 papers have been published confirming the important role of HLA-G in the regulation of the human immune system, indicating HLA-G antigens as a prognostic factor in the development of various pathological conditions. HLA-G proteins have been shown to be involved in the immune regulation of the pathogenesis of autoimmune and allergic diseases, such as gastrointestinal, skin, neurological and rheumatological diseases, as well as in the pathology of pregnancy.
Conclusion. The level of sHLA-G is particularly significant in the development of inflammatory processes in allergic diseases, in particular bronchial asthma, which opens up new opportunities for its use as an important marker of inflammation. In addition, sHLA-G, as an accessible diagnostic indicator, can be effectively introduced into the healthcare system, thereby aiding in the prediction of allergic diseases and monitoring maintenance therapy.
About the Author
A. A. Mkhitaryan
Yerevan State Medical University named after Mkhitar Heratsi
Armenia
Armenia
2 Koryun Str., Yerevan, 0025
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Review
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Mkhitaryan A.A. Predictors of Recurrent Wheezing in Young Children. Title. 2024;23(6):88-92. (In Russ.) https://doi.org/10.31550/1727-2378-2024-23-6-88-92
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