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Risks of Venous Thromboembolic Events and the Great Obstetric Syndromes

https://doi.org/10.31550/1727-2378-2023-22-1-33-39

Abstract

Aim: Based on the study of the history, course of pregnancy and childbirth, to assess the risks of venous thromboembolic events among women with major obstetric syndromes.

Design: Retrospective cohort study using the continuum sampling method.

Materials and methods. 200 birth histories were analyzed: group 1 — 55 women with great obstetric syndromes, group 2 — 145 pregnant without them. The history of women, pregnancy outcomes were studied, and an analysis of the risks of venous thromboembolic complications was carried out.

Results. Anamnestic risk factors for major obstetric syndromes were a family history aggravated by early thromboembolic events (RR = 3,13; 95% CI: 1,34–7,30), unemployed status (RR = 1,73; 95% CI: 1,32–2,65), preeclampsia in the past (RR = 23,46; 95% CI: 1,28–428,80), first pregnancy (RR = 1,63; 95% CI: 1,04–2,55), chronic arterial hypertension (RR = 8,45; 95% CI: 1,76–40,66). There was a significant increase in the risk of venous thromboembolic complications in patients of group 1 during pregnancy (1 (1–2) points; p < 0.001) and in the postpartum period (3 (1–4) points; p < 0.001).

Conclusion. Prognostic markers of great obstetric syndromes were aggravated family and personal obstetric anamnesis, parity, low social status, chronic arterial hypertension. A significant increase in the risk of venous thromboembolic complications in pregnant women and puerperas with major obstetric syndromes was revealed.

About the Authors

V. F. Dolgushina
South-Ural State Medical University
Russian Federation

64 Vorovskoy Str., Chelyabinsk, 454092



E. G. Syundyukova
South-Ural State Medical University
Russian Federation

64 Vorovskoy Str., Chelyabinsk, 454092



V. S. Chulkov
South-Ural State Medical University
Russian Federation

64 Vorovskoy Str., Chelyabinsk, 454092



K. A. Unigovskaya
South-Ural State Medical University
Russian Federation

64 Vorovskoy Str., Chelyabinsk, 454092



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Dolgushina V.F., Syundyukova E.G., Chulkov V.S., Unigovskaya K.A. Risks of Venous Thromboembolic Events and the Great Obstetric Syndromes. Title. 2023;22(1):33-39. (In Russ.) https://doi.org/10.31550/1727-2378-2023-22-1-33-39

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ISSN 1727-2378 (Print)
ISSN 2713-2994 (Online)