docruДоктор.РуTitle1727-23782713-2994ООО "ГК "РУСМЕДИКАЛ"10.31550/1727-2378-2022-21-7-12-19docru-78Research ArticleПУЛЬМОНОЛОГИЯPULMONOLOGYФакторы риска, диагностика, скрининг и терапия легочной гипертензии у детей с бронхолегочной дисплазиейRisk Factors, Diagnosis, Screening and Therapy of Pulmonary Hypertension in Children with Bronchopulmonary DysplasiaОвсянниковД. Ю.OvsyannikovD. Yu.

Овсянников Дмитрий Юрьевич — д. м. н., доцент, заведующий кафедрой педиатрии; врач-пульмонолог

117198, Россия, г. Москва, ул. Миклухо-Маклая, д. 6

6 Miklouho-Maclay St., Moscow,  117198

1/9 4-y Dobrynenskiy per., Moscow, 119049

mdovsyannikov@yahoo.comhttps://orcid.org/0000-0002-3219-2145ДегтярёваЕ. А.DegtyarevaE. A.

Дегтярёва Елена Александровна — д. м. н., профессор, заведующая кафедрой детской кардиологии с курсами сердечно-сосудистой и эндоваскулярной хирургии врожденных пороков сердца и перинатальной ультразвуковой диагностики факультета непрерывного  медицинского образования, профессор кафедры педиатрии

117198, Россия, г. Москва, ул. Миклухо-Маклая, д. 6

6 Miklouho-Maclay St., Moscow, 117198

dgp48@yandex.ruhttps://orcid.org/0000-0003-4140-8777МирошниченкоВ. П.MiroshnichenkoV. P.

Мирошниченко Владимир Петрович — врач — детский кардиолог отделения экстренной кардиохирургии и интенсивной кардиологии

г. Москва, 4-й Добрынинский пер., д. 1/9

1/9 4-y Dobrynenskiy per., Moscow, 119049

vladi.miroshnichenko@gmail.comhttps://orcid.org/0000-0002-2082-5531СтрельниковаВ. А.StrellnikovaV. A.

Стрельникова Валерия Алексеевна — аспирант кафедры педиатрии

117198, г. Москва, ул. Миклухо-Маклая, д. 6

6 Miklouho-Maclay St., Moscow, 117198

doc.strelnikova@mail.ruhttps://orcid.org/0000-0003-4018-6287АбрамянМ. А.AbramyanM. A.

Абрамян Михаил Арамович  — д. м. н., профессор кафедры педиатрии; руководитель кардиохирургической службы

117198, г. Москва, ул. Миклухо-Маклая, д. 6

6 Miklouho-Maclay St., Moscow, 117198

1/9 4-y Dobrynenskiy per., Moscow, 119049

mabramyan@morozdgkb.ruМедицинский институт ФГАОУ ВО РУДН; ГБУЗ «Морозовская ДГКБ ДЗМ»РоссияPeoples’ Friendship University of Russia (a Federal Government Autonomous Educational Institution of Higher Education; Morozovskaya Children Clinical Hospital of Moscow Department of Public HealthRussian FederationМедицинский институт ФГАОУ ВО РУДНРоссияPeoples’ Friendship University of Russia (a Federal Government Autonomous Educational Institution of Higher EducationRussian FederationГБУЗ «Морозовская ДГКБ ДЗМ»РоссияMorozovskaya Children Clinical Hospital of Moscow Department of Public HealthRussian Federation202215022025217ПЕДИАТРИЯ1219Copyright © Овсянников Д.Ю., Дегтярёва Е.А., Мирошниченко В.П., Стрельникова В.А., Абрамян М.А., 20252025Овсянников Д.Ю., Дегтярёва Е.А., Мирошниченко В.П., Стрельникова В.А., Абрамян М.А.Ovsyannikov D.Y., Degtyareva E.A., Miroshnichenko V.P., Strellnikova V.A., Abramyan M.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://docru.elpub.ru/jour/article/view/78Цель обзора

Цель обзора: представить актуальную информацию об опасном осложнении бронхолегочной дисплазии (БЛД) — легочной гипертензии (ЛГ), основанную на отечественных и зарубежных согласительных документах и результатах собственных исследований.

Основные положения

Основные положения. БЛД нередко осложняется ЛГ, ассоциированной с анте-, пери- и постнатальными факторами риска (ФР). Наличие ФР, дыхательная недостаточность, бронхиальная обструкция у ребенка с БЛД являются основаниями для исключения ЛГ в ходе эхокардиографии, которая позволяет выявить повышение давления в легочной артерии, косвенные признаки ЛГ. Обязательный метод лечения ЛГ у детей с БЛД — кислородотерапия, при ее недостаточной эффективности последовательно применяют силденафил, бозен тан, ингаляции оксида азота.

Заключение

Заключение. Поскольку клинические проявления ЛГ у детей с БЛД неотличимы от симптомов основного заболевания легких, необхо димо проводить скрининг ЛГ для своевременного назначения терапии этого осложнения.

Objective of the Review

Objective of the Review: on the basis of domestic and foreign conciliation documents and the results of our own research, to present up-to date information about a dangerous complication of bronchopulmonary dysplasia - pulmonary hypertension.

Key Points

Key Points: pulmonary hypertension is a common complication of bronchopulmonary dysplasia, which has antenatal, perinatal and postnatal risk factors. The presence of risk factors, respiratory failure, bronchial obstruction in a child with bronchopulmonary dysplasia is the basis for excluding pulmonary hypertension by echocardiography, which allows to detect an increase in pressure in the pulmonary artery, indirect signs of pulmonary hypertension. An obligatory method of treatment of pulmonary hypertension in children with bronchopulmonary dysplasia is oxygen therapy. With insufficient effectiveness of oxygen therapy, treatment is sequentially carried out with sildenafil, bosentan, and nitric oxide.

Conclusion

Conclusion: Since the clinical manifestations of pulmonary hypertension in children with bronchopulmonary dysplasia are indistinguishable from the symptoms of the underlying lung disease, timely screening of this complication and the appointment of therapy are necessary.

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The authors declare that there are no conflicts of interest present.