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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">docru</journal-id><journal-title-group><journal-title xml:lang="ru">Доктор.Ру</journal-title><trans-title-group xml:lang="en"><trans-title>Title</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-2378</issn><issn pub-type="epub">2713-2994</issn><publisher><publisher-name>ООО "ГК "РУСМЕДИКАЛ"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31550/1727-2378-2022-21-6-41-44</article-id><article-id custom-type="elpub" pub-id-type="custom">docru-48</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГАСТРОЭНТЕРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>GASTROENTEROLOGY</subject></subj-group></article-categories><title-group><article-title>Сложности диагностики болезней пищевода: спонтанный разрыв пищевода (синдром Бурхаве)</article-title><trans-title-group xml:lang="en"><trans-title>The Difficulties of Diagnostics of Diseases of the Oesophagus: Spontaneous Rupture of the Oesophagus (Boerhaave's Syndrome)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9202-424X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аснер</surname><given-names>Т. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Asner</surname><given-names>T. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аснер Татьяна Викторовна - к. м. н., доцент кафедры пропедевтики внутренних болезней</p><p>664003, г. Иркутск, ул. Красного Восстания, д. 1</p></bio><bio xml:lang="en"><p>1 Krasnoe Vosstanie Str., Irkutsk, 664003</p></bio><email xlink:type="simple">a1951t@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2708-3972</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Калягин</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Kalyagin</surname><given-names>A. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Калягин Алексей Николаевич - д. м. н., профессор, проректор по лечебной работе и последипломному образованию, заведующий кафедрой пропедевтики внутренних болезней; врач-кардиолог кардиологического отделения</p><p>664003, г. Иркутск, ул. Красного Восстания, д. 1</p></bio><bio xml:lang="en"><p>1 Krasnoe Vosstanie Str., Irkutsk, 664003</p><p>118 Baykalskaya Str., Irkutsk, 664046</p></bio><email xlink:type="simple">akalagin@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5587-5344</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Киселёва</surname><given-names>Е. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Kiseleva</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Киселёва Елизавета Радионовна - врач-кардиолог кардиологического отделения</p><p>664046, г. Иркутск, Байкальская ул., д. 118</p></bio><bio xml:lang="en"><p>1 Krasnoe Vosstanie Str., Irkutsk, 664003</p></bio><email xlink:type="simple">zizabetka2510@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6440-1485</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синькова</surname><given-names>Г. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinkova</surname><given-names>G. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Синькова Галина Михайловна - д. м. н., заместитель министра здравоохранения Иркутской области, профессор кафедры пропедевтики внутренних болезней</p><p>664003, г. Иркутск, ул. Красного Восстания, д. 1</p></bio><bio xml:lang="en"><p>1 Krasnoe Vosstanie Str., Irkutsk, 664003</p></bio><email xlink:type="simple">gsink2014@outlook.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7242-9346</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Синьков</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sinkov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Синьков Андрей Владимирович - д. м. н., профессор кафедры пропедевтики внутренних болезней</p><p>664003, г. Иркутск, ул. Красного Восстания, д. 1</p></bio><bio xml:lang="en"><p>1 Krasnoe Vosstanie Str., Irkutsk, 664003</p></bio><email xlink:type="simple">asinkov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Иркутский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education “Irkutsk State Medical University” of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБОУ ВО «Иркутский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education “Irkutsk State Medical University” of the Ministry of Healthcare of the Russian Federation; Regional State Budgetary Institution of Health “Irkutsk Municipal Clinical Hospital No. 1”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ОГБУЗ «Иркутская городская клиническая больница № 1»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Federal State Budgetary Educational Institution of Higher Education “Irkutsk State Medical University” of the Ministry of Healthcare of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>14</day><month>02</month><year>2025</year></pub-date><volume>21</volume><issue>6</issue><issue-title>ТЕРАПИЯ</issue-title><fpage>41</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аснер Т.В., Калягин А.Н., Киселёва Е.Р., Синькова Г.М., Синьков А.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Аснер Т.В., Калягин А.Н., Киселёва Е.Р., Синькова Г.М., Синьков А.В.</copyright-holder><copyright-holder xml:lang="en">Asner T.V., Kalyagin A.N., Kiseleva E.R., Sinkova G.M., Sinkov A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://docru.elpub.ru/jour/article/view/48">https://docru.elpub.ru/jour/article/view/48</self-uri><abstract><p>Цель статьи: представить клиническое наблюдение спонтанного разрыва пищевода (синдрома Бурхаве).Основные положения. Особенностью данного наблюдения стало поступление больной в клинику с нарушением сознания, что не позволило выявить классическую триаду признаков этого патологического состояния и выставить диагноз при жизни. В анамнезе у пациентки не было болезней пищевода, неизвестно, злоупотребляла ли она алкоголем. Фиброгастродуоденоскопия не показала достоверные признаки разрыва пищевода. Отсутствие четких клинических симптомов, подробного анамнеза привело к тому, что не была назначена рентгеноскопия пищевода с контрастированием его бариевой взвесью, которая дает наиболее информативные доказательства синдрома Бурхаве.Заключение. Авторы призывают врачей включать синдром Бурхаве в дифференциальный диагноз у пациентов, которые поступают с доминирующей клиникой нарушения сознания в отсутствие явных лабораторно-инструментальных изменений.</p></abstract><trans-abstract xml:lang="en"><p>Objective of the Paper: To present a clinical observation of a spontaneous rupture of the esophagus (Boerhaave's syndrome).Key points. A feature of this observation was the patient's admission to the clinic in a disturbance of consciousness, which did not allow to identify the classic triad of signs of this pathological condition and make a diagnosis during the patient's life. The patient had no history of diseases of the esophagus, it is not known whether she abused alcohol. Fibrogastroduodenoscopy did not show reliable signs of rupture of the esophagus. The absence of clear clinical symptoms and a detailed history led to the fact that fluoroscopy of the esophagus with its contrasting barium suspension, which provides the most informative evidence of Boerhaave's syndrome, was not prescribed.Conclusion. The authors urge physicians to include Boerhaave's syndromein the differential diagnosis in patients who are admitted with a dominant clinic of impaired consciousness in the absence of obvious laboratory instrumental changes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром Бурхаве</kwd><kwd>спонтанный разрыв пищевода</kwd><kwd>поражение пищевода</kwd><kwd>перфорация пищевода</kwd><kwd>ожирение</kwd><kwd>нарушение сознания</kwd><kwd>клиническое наблюдение</kwd><kwd>трудный диагноз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Boerhaave's syndrome</kwd><kwd>spontaneous rupture of the esophagus</kwd><kwd>damage to the esophagus</kwd><kwd>oesophageal perforation</kwd><kwd>obesity</kwd><kwd>violation of consciousness</kwd><kwd>clinical observation</kwd><kwd>difficult diagnosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Matsuura N., Saitou K. 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