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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">docru</journal-id><journal-title-group><journal-title xml:lang="ru">Доктор.Ру</journal-title><trans-title-group xml:lang="en"><trans-title>Title</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-2378</issn><issn pub-type="epub">2713-2994</issn><publisher><publisher-name>ООО "ГК "РУСМЕДИКАЛ"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31550/1727-2378-2022-21-6-25-28</article-id><article-id custom-type="elpub" pub-id-type="custom">docru-37</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Клиническое наблюдение новой коронавирусной инфекции с развитием сердечно-сосудистых осложнений на фоне коморбидной патологии</article-title><trans-title-group xml:lang="en"><trans-title>Clinical Case of the Novel Coronavirus Infection with the Development of Cardiovascular Complications Against the Background of Comorbid Pathology</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6489-9938</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кутелев</surname><given-names>Г. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kutelev</surname><given-names>G. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кутелев Геннадий Геннадьевич - к. м. н., докторант кафедры военно-морской терапии</p><p>198013, г. Санкт-Петербург, Загородный пр-т, д. 47</p></bio><bio xml:lang="en"><p>6 Academician Lebedev Str., St. Petersburg, 194044</p></bio><email xlink:type="simple">gena08@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9232-6459</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мирзоев</surname><given-names>Н. Т.</given-names></name><name name-style="western" xml:lang="en"><surname>Mirzoev</surname><given-names>N. T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мирзоев Никита Тагирович - слушатель ординатуры по специальности «терапия»</p><p>194044, г. Санкт-Петербург, ул. Академика Лебедева, д. 6</p></bio><bio xml:lang="en"><p>6 Academician Lebedev Str., St. Petersburg, 194044</p></bio><email xlink:type="simple">mirsoev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2310-4518</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванов Владимир Владимирович - к. м. н., начальник пульмонологического отделения 1-й клиники (терапии усовершенствования врачей)</p><p>194044, г. Санкт-Петербург, ул. Академика Лебедева, д. 6</p></bio><bio xml:lang="en"><p>6 Academician Lebedev Str., St. Petersburg, 194044</p></bio><email xlink:type="simple">sea-89@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1363-6860</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черкашин</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Cherkashin</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Черкашин Дмитрий Викторович - д. м. н., профессор, начальник кафедры военно-морской терапии</p><p>198013, г. Санкт-Петербург, Загородный пр-т, д. 47</p></bio><bio xml:lang="en"><p>6 Academician Lebedev Str., St. Petersburg, 194044</p></bio><email xlink:type="simple">cherkashin_dmitr@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2180-6885</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макиев</surname><given-names>Р. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Makiev</surname><given-names>R. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Макиев Руслан Гайозович - д. м. н., заместитель начальника академии по учебной работе</p><p>194044, г. Санкт-Петербург, ул. Академика Лебедева, д. 6</p></bio><bio xml:lang="en"><p>6 Academician Lebedev Str., St. Petersburg, 194044</p></bio><email xlink:type="simple">moro5555@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тедеев</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Tedeev</surname><given-names>T. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тедеев Тамерлан Геннадьевич - слушатель ординатуры по специальности «терапия»</p><p>194044, г. Санкт-Петербург, ул. Академика Лебедева, д. 6</p></bio><bio xml:lang="en"><p>6 Academician Lebedev Str., St. Petersburg, 194044</p></bio><email xlink:type="simple">ossetia1969@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБВОУ ВО «Военно-медицинская академия имени С.М. Кирова» Министерства обороны Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.M. Kirov Military Medical Academy (a Federal Government-funded Military Educational Institution of Higher Education)</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Тедеев Тамерлан Геннадьевич / Tedeev, T.G. — слушатель ординатуры по специальности</institution><country>Россия</country></aff><aff xml:lang="en"><institution>S.M. Kirov Military Medical Academy (a Federal Government-funded Military Educational Institution of Higher Education)</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>13</day><month>02</month><year>2025</year></pub-date><volume>21</volume><issue>6</issue><issue-title>ТЕРАПИЯ</issue-title><fpage>25</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кутелев Г.Г., Мирзоев Н.Т., Иванов В.В., Черкашин Д.В., Макиев Р.Г., Тедеев Т.Г., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Кутелев Г.Г., Мирзоев Н.Т., Иванов В.В., Черкашин Д.В., Макиев Р.Г., Тедеев Т.Г.</copyright-holder><copyright-holder xml:lang="en">Kutelev G.G., Mirzoev N.T., Ivanov V.V., Cherkashin D.V., Makiev R.G., Tedeev T.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://docru.elpub.ru/jour/article/view/37">https://docru.elpub.ru/jour/article/view/37</self-uri><abstract><p>Цель статьи: продемонстрировать клиническое наблюдение тяжелого течения новой коронавирусной инфекции с развитием сердечно-сосудистых осложнений на фоне сопутствующих коморбидных заболеваний.Основные положения. Представлен случай новой коронавирусной инфекции с описанием клинического течения и результатов лабораторно-инструментального обследования. В клинической картине, кроме массивного поражения легочной ткани, по данным компьютерной томографии, наблюдались впервые возникшие ишемический инсульт, фибрилляция предсердий и инфаркт миокарда 2 типа, протекавшие на фоне ожирения, сахарного диабета 2 типа и аутоиммунного тиреоидита.Заключение. Полиморфизм клинической картины и различные варианты манифестации новой коронавирусной инфекции, в ряде случаев полисистемного характера, требуют своевременной диагностики данного заболевания и выявления на ранних этапах его потенциальных осложнений, развивающихся в остром периоде, особенно у лиц старшей возрастной группы.</p></abstract><trans-abstract xml:lang="en"><p>Objective of the Paper: To demonstrate a clinical case of a severe course of the novel coronavirus infection with the development of cardiovascular complications against the background of concomitant comorbid diseases.Key points. A case of a novel coronavirus infection is presented with a description of the clinical course and the results of laboratory and instrumental examination. In the clinical picture, in addition to massive damage of the lung tissue, according to computed tomography, firsttime ischemic stroke, atrial fibrillation, and type 2 myocardial infarction were observed, which occurred against the background of obesity, type 2 diabetes mellitus and autoimmune thyroiditis.Conclusion. The polymorphism of the clinical picture and the various variants of manifestation of a novel coronavirus infection, taking in some cases a polysystemic character, require doctors to diagnose the disease in a timely manner and identify its potential complications at an early stage, developing in the acute period, especially in the older age group.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>новая коронавирусная инфекция</kwd><kwd>SARS-CoV-2</kwd><kwd>фибрилляция предсердий</kwd><kwd>ишемический инсульт</kwd><kwd>инфаркт миокарда 2 типа</kwd></kwd-group><kwd-group xml:lang="en"><kwd>novel coronavirus disease</kwd><kwd>SARS-CoV-2</kwd><kwd>atrial fibrillation</kwd><kwd>ischemic stroke</kwd><kwd>type 2 myocardial infarction</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Wiersinga W.J., Rhodes A., Cheng A.C., Peacock S.J. et al. Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): a review. JAMA. 2020; 324(8): 782–93. DOI: 10.1001/jama.2020.12839COVID-19</mixed-citation><mixed-citation xml:lang="en">Wiersinga W.J., Rhodes A., Cheng A.C., Peacock S.J. et al. Pathophysiology, transmission, diagnosis, and treatment of coronavirus disease 2019 (COVID-19): a review. JAMA. 2020; 324(8): 782–93. DOI: 10.1001/jama.2020.12839COVID-19</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Li H., Liu S.M., Yu X.H., Tang S.L. et al. Coronavirus disease 2019 (COVID-19): current status and future perspectives. Int. J. Antimicrob. Agents. 2020; 55(5): 105951. DOI: 10.1016/j.ijantimicag.2020.105951</mixed-citation><mixed-citation xml:lang="en">Li H., Liu S.M., Yu X.H., Tang S.L. et al. Coronavirus disease 2019 (COVID-19): current status and future perspectives. Int. J. Antimicrob. Agents. 2020; 55(5): 105951. DOI: 10.1016/j.ijantimicag.2020.105951</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Long B., Brady W., Koyfman A., Gottlieb M. Cardiovascular complications in COVID-19. Am. J. Emerg. Med. 2020; 38(7): 1504–7. DOI: 10.1016/j.ajem.2020.04.048</mixed-citation><mixed-citation xml:lang="en">Long B., Brady W., Koyfman A., Gottlieb M. Cardiovascular complications in COVID-19. Am. J. Emerg. Med. 2020; 38(7): 1504–7. DOI: 10.1016/j.ajem.2020.04.048</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Мирзоев Н.Т., Кутелев Г.Г., Пугачев М.И. Киреева Е.Б. Сердечно-сосудистые осложнения у пациентов, перенесших COVID-19. Вестник Российской военно-медицинской академии. 2022; 24(1): 199–208.</mixed-citation><mixed-citation xml:lang="en">Mirzoev N.T., Kutelev G.G., Pugachev M.I., Kireeva E.B. Cardiovascular complications in patients after coronavirus disease-2019. Bulletin of the Russian Military Medical Academy. 2022; 24(1): 199–208. (in Russian). DOI: 10.17816/brmma90733</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Фисун А.Я., Лобзин Ю.В., Черкашин Д.В., Тыренко В.В. и др. Механизмы поражения сердечно-сосудистой системы при COVID-19. Вестник РАМН. 2021; 76(3): 287–97.</mixed-citation><mixed-citation xml:lang="en">Fisun A.Ya., Lobzin Yu.V., Cherkashin D.V., Tyrenko V.V. et al. Mechanisms of damage to the cardiovascular system in COVID-19. Annals of the Russian Academy of Medical Sciences. 2021; 76(3): 287–97. (in Russian). DOI: 10.15690/vramn1474</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Крюков Е.В., ред. Патогенез и клинические проявления поражения сердечно-сосудистой системы у пациентов с новой коронавирусной инфекцией (COVID-19). СПб.: Веда Принт; 2021. 36 с.</mixed-citation><mixed-citation xml:lang="en">Kryukov E.V., ed. Pathogenesis and clinical manifestations of cardiovascular disorders in patients with the novel coronavirus infection (COVID-19). St. Petersburg: Veda Print; 2021. 36 p. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Rashidi F., Barco S., Kamangar F., Heresi G.A. et al. Incidence of symptomatic venous thromboembolism following hospitalization for coronavirus disease 2019: prospective results from a multi-center study. Thromb. Res. 2021; 198: 135–8. DOI: 10.1016/j.thromres.2020.12.001</mixed-citation><mixed-citation xml:lang="en">Rashidi F., Barco S., Kamangar F., Heresi G.A. et al. Incidence of symptomatic venous thromboembolism following hospitalization for coronavirus disease 2019: prospective results from a multi-center study. Thromb. Res. 2021; 198: 135–8. DOI: 10.1016/j.thromres.2020.12.001</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Li P., Zhao W., Kaatz S., Latack K. et al. Factors associated with risk of postdischarge thrombosis in patients with COVID-19. JAMA Netw. Open. 2021; 4(11): e2135397. DOI: 10.1001/jamanetworkopen.2021.35397</mixed-citation><mixed-citation xml:lang="en">Li P., Zhao W., Kaatz S., Latack K. et al. Factors associated with risk of postdischarge thrombosis in patients with COVID-19. JAMA Netw. Open. 2021; 4(11): e2135397. DOI: 10.1001/jamanetworkopen.2021.35397</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Khunti K., Del Prato S., Mathieu C., Kahn S.E. et al. COVID-19, hyperglycemia, and newonset diabetes. Diabetes Care. 2021; 44(12): 2645–55. DOI: 10.2337/dc21-1318</mixed-citation><mixed-citation xml:lang="en">Khunti K., Del Prato S., Mathieu C., Kahn S.E. et al. COVID-19, hyperglycemia, and newonset diabetes. Diabetes Care. 2021; 44(12): 2645–55. DOI: 10.2337/dc21-1318</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Tutal E., Ozaras R., Leblebicioglu H. Systematic review of COVID-19 and autoimmune thyroiditis. Travel Med. Infect. Dis. 2022; 47: 102314. DOI: 10.1016/j.tmaid.2022.102314</mixed-citation><mixed-citation xml:lang="en">Tutal E., Ozaras R., Leblebicioglu H. Systematic review of COVID-19 and autoimmune thyroiditis. Travel Med. Infect. Dis. 2022; 47: 102314. DOI: 10.1016/j.tmaid.2022.102314</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Петунина Н.А., Эль-Тарави Я.А., Суркова А.Ю., Мартиросян Н.С. Заболевания щитовидной железы и COVID-19. Доктор.Ру. 2021; 20(2): 6–10.</mixed-citation><mixed-citation xml:lang="en">Petunina N.A., Al Taravi Ya.A., Surkova A.Yu., Martirosyan N.S. Thyroid disorders and COVID-19. Doctor.Ru. 2021; 20(2): 6–10. (in Russian). DOI: 10.31550/1727-2378-2021-20-2-6-10</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Zhou F., Yu T., Du R., Fan G. et al. Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395(10229): 1054–62. DOI: 10.1016/S0140-6736(20)30566-3</mixed-citation><mixed-citation xml:lang="en">Zhou F., Yu T., Du R., Fan G. et al. Clinical course and risk factors for mortality of adult in patients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet. 2020; 395(10229): 1054–62. DOI: 10.1016/S0140-6736(20)30566-3</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Li Y., Li M., Wang M., Zhou Y. et al. Acute cerebrovascular disease following COVID-19: a single center, retrospective, observational study. Stroke Vasc. Neurol. 2020; 5(3): 279–84. DOI: 10.1136/svn-2020-000431</mixed-citation><mixed-citation xml:lang="en">Li Y., Li M., Wang M., Zhou Y. et al. Acute cerebrovascular disease following COVID-19: a single center, retrospective, observational study. Stroke Vasc. Neurol. 2020; 5(3): 279–84. DOI: 10.1136/svn-2020-000431</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Talanas G., Dossi F., Parodi G. Type 2 myocardial infarction in patients with coronavirus disease 2019. J. Cardiovasc. Med. (Hagerstown). 2021; 22(7): 603–5. DOI: 10.2459/JCM.0000000000001136</mixed-citation><mixed-citation xml:lang="en">Talanas G., Dossi F., Parodi G. Type 2 myocardial infarction in patients with coronavirus disease 2019. J. Cardiovasc. Med. (Hagerstown). 2021; 22(7): 603–5. DOI: 10.2459/JCM.0000000000001136</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
