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<article article-type="other" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">docru</journal-id><journal-title-group><journal-title xml:lang="ru">Доктор.Ру</journal-title><trans-title-group xml:lang="en"><trans-title>Title</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-2378</issn><issn pub-type="epub">2713-2994</issn><publisher><publisher-name>ООО "ГК "РУСМЕДИКАЛ"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31550/1727-2378-2024-23-5-79-82</article-id><article-id custom-type="elpub" pub-id-type="custom">docru-309</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ ОПЫТ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>Клинический случай мембранозной дисменореи у женщины с синдромом поликистозных яичников</article-title><trans-title-group xml:lang="en"><trans-title>A Case Report of Membranous Dysmenorrhoea in Woman with Polycystic Ovary Syndrome</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3464-6761</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гродницкая</surname><given-names>Е. Э.</given-names></name><name name-style="western" xml:lang="en"><surname>Grodnitskaya</surname><given-names>E. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гродницкая Елена Эдуардовна — к. м. н., врач – акушер-гинеколог Клинического госпиталя MD GROUP на Севастопольском; врач – акушер-гинеколог МНОИ МГУ</p><p>117209, г. Москва, Севастопольский пр-т, д. 24, корп. 1</p></bio><bio xml:lang="en"><p>24 Sevastopol Ave., built. 1, Moscow, 117209</p><p>27 Lomonosov Ave., built. 10, Moscow, 119192</p></bio><email xlink:type="simple">elena1778@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карабанович</surname><given-names>Я. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Karabanovich</surname><given-names>Ya. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Карабанович Янина Владимировна — к. м. н., врач – акушер-гинеколог, заведующая приемным отделением</p><p>117209, г. Москва, Севастопольский пр-т, д. 24, корп. 1</p></bio><bio xml:lang="en"><p>24 Sevastopol Ave., built. 1, Moscow, 117209</p></bio><email xlink:type="simple">ykarabanovich@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0175-1968</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Курцер</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Кurtser</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Курцер Марк Аркадьевич — д. м. н., профессор, академик РАН, заведующий кафедрой акушерства и гинекологии имени академика Г.М. Савельевой педиатрического факультета ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России; генеральный директор Группы компаний «Мать и дитя»</p><p>117209, г. Москва, Севастопольский пр-т, д. 24А</p></bio><bio xml:lang="en"><p>1 Ostrovitianov Str., Moscow, 117513</p><p>24A Sevastopol Ave., Moscow, 117209</p></bio><email xlink:type="simple">m.kurtser@mcclinics.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Клинический госпиталь MD GROUP на Севастопольском Группы компаний «Мать и дитя»; Медицинский научно-образовательный институт Московского государственного университета имени М.В. Ломоносова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical hospital "MD GROUP", Group of companies "Mother and child"; Lomonosov Moscow State University Medical Institute</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Клинический госпиталь MD GROUP на Севастопольском Группы компаний «Мать и дитя»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Clinical hospital "MD GROUP", Group of companies "Mother and child"</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГАОУ ВО «Российский национальный исследовательский медицинский университет имени Н.И. Пирогова» Минздрава России; Группа компаний «Мать и дитя»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.I. Pirogov Russian National Research Medical University; MD Medical Group "Mother and Child"</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2025</year></pub-date><volume>23</volume><issue>5</issue><issue-title>ГИНЕКОЛОГИЯ</issue-title><fpage>79</fpage><lpage>82</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гродницкая Е.Э., Карабанович Я.В., Курцер М.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Гродницкая Е.Э., Карабанович Я.В., Курцер М.А.</copyright-holder><copyright-holder xml:lang="en">Grodnitskaya E.E., Karabanovich Y.V., Кurtser M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://docru.elpub.ru/jour/article/view/309">https://docru.elpub.ru/jour/article/view/309</self-uri><abstract><sec><title>Цель статьи</title><p>Цель статьи. Представить клинический случай мембранозной дисменореи у пациентки с синдромом поликистозных яичников.</p></sec><sec><title>Основные положения</title><p>Основные положения. Мембранозная дисменорея — редкое гинекологическое заболевание, характеризующееся спонтанным отслоением эндометрия и последующей его экспульсией в виде единого фрагмента, сохраняющего форму полости матки. В литературе описано всего несколько случаев мембранозной дисменореи: в основном у молодых женщин, принимающих комбинированные гормональные контрацептивы или прогестагены.</p><p>В представленном клиническом наблюдении у 30-летней женщины с синдромом поликистозных яичников в конце первого цикла приема контрацептива, содержащего этинилэстрадиол и диеногест, развились выраженные боли схваткообразного характера в подчревном отделе с последующим изгнанием из влагалища ткани, при гистологическом исследовании которой был подтвержден диагноз мембранозной дисменореи.</p></sec><sec><title>Заключение</title><p>Заключение. Недостаток научных данных о мембранозной дисменорее, отсутствие ее описания в медицинских учебных материалах способствуют гиподиагностике этого состояния. Необходимы дальнейшие исследования для прояснения этиологии и патогенеза данного заболевания.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To present a case report of membranous dysmenorrhoea in woman with polycystic ovary syndrome.</p></sec><sec><title>Key points</title><p>Key points. Membranous dysmenorrhea is defined as sudden sloughing of thickened endometrium as a whole with the shape of the uterine cavity. It’s more common in young females who were on either combined hormonal contraceptive or progestagen. Membranous dysmenorrhea is a rare gynecologic disorder with only a few documented cases. Because this entity is rarely mentioned in the medical literature, the purpose of this report is to describe such case.</p><p>In presented clinical case report 30-year-old woman with polycystic ovary syndrome at the end of first cycle of treatment with combined oral contraceptive, containing ethynilestradiol and dienogest, developed acute cramping hypogastric pain followed by discharge a tissue from vagina. It's histopathological exam was performed with a clear diagnosis of membranous dysmenorrhoea.</p></sec><sec><title>Conclusion</title><p>Conclusion. The medical knowledge, due to the lack of description of this entity in current textbooks, contributes to its underdiagnosis. More studies are needed to clarify the aetiology and the pathophysiology of this pathologic condition.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>мембранозная дисменорея</kwd><kwd>женщины</kwd><kwd>синдром поликистозных яичников</kwd></kwd-group><kwd-group xml:lang="en"><kwd>membranous dysmenorrhea</kwd><kwd>women</kwd><kwd>polycystic ovary syndrome</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Nunes R.D., Pissetti V.C. Membranous dysmenorrhea — case report. Obstet. Gynecol. Cases Rev. 2015;2:4. DOI: 10.23937/2377-9004/1410042</mixed-citation><mixed-citation xml:lang="en">Nunes R.D., Pissetti V.C. Membranous dysmenorrhea — case report. Obstet. Gynecol. Cases Rev. 2015;2:4. DOI: 10.23937/2377-9004/1410042</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Omar H.A., Smith S.J. 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