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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">docru</journal-id><journal-title-group><journal-title xml:lang="ru">Доктор.Ру</journal-title><trans-title-group xml:lang="en"><trans-title>Title</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-2378</issn><issn pub-type="epub">2713-2994</issn><publisher><publisher-name>ООО "ГК "РУСМЕДИКАЛ"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31550/1727-2378-2023-22-7-24-30</article-id><article-id custom-type="elpub" pub-id-type="custom">docru-299</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЭНДОКРИНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ENDOCRINOLOGY</subject></subj-group></article-categories><title-group><article-title>Эпидемиология ожирения у детей и подростков  Новосибирской области в 2018–2022 гг.</article-title><trans-title-group xml:lang="en"><trans-title>Epidemiology of Obesity in Children  and Adolescents of the Novosibirsk Region in 2018–2022</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5012-0364</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Коваренко</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kovarenko</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Коваренко Маргарита Анатольевна — к. м. н., доцент кафедры педиатрии факультета повышения квалификации и профессиональной переподготовки врачей </p><p>630091,  г. Новосибирск, Красный пр-т, д. 52</p></bio><bio xml:lang="en"><p>52 Krasny Ave., Novosibirsk,  630091</p></bio><email xlink:type="simple">grun-wald@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3250-3107</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кондюрина</surname><given-names>Е. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Kondyurina</surname><given-names>E. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кондюрина Елена Геннадьевна — д. м. н., профессор, заведующая кафедрой педиатрии факультета повышения квалификации и профессиональной переподготовки врачей </p><p>630091,  г. Новосибирск, Красный пр-т, д. 52</p></bio><bio xml:lang="en"><p>52 Krasny Ave., Novosibirsk,  630091</p></bio><email xlink:type="simple">condur@ngs.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0344-9412</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Зеленская</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zelenskaia</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Зеленская Вера Викторовна  — д. м. н., профессор кафедры педиатрии факультета повышения квалификации и профессиональной переподготовки врачей </p><p>630091,  г. Новосибирск, Красный пр-т, д. 52</p></bio><bio xml:lang="en"><p>52 Krasny Ave., Novosibirsk,  630091</p></bio><email xlink:type="simple">v.zelenskaya@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Анохина</surname><given-names>Т. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Anokhina</surname><given-names>T. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Анохина Татьяна Юрьевна — к. м. н., заместитель министра здравоохранения Новосибирской области, ассистент кафедры педиатрии факультета повышения квалификации и профессиональной переподготовки врачей</p><p>630091,  г. Новосибирск, Красный пр-т, д. 52</p></bio><bio xml:lang="en"><p>52 Krasny Ave., Novosibirsk,  630091</p></bio><email xlink:type="simple">anochinaty@ngs.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7958-0081</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пилипенко</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pilipenko</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пилипенко Оксана Владимировна  — руководитель; ассистент кафедры педиатрии факультета повышения квалификации и профессиональной переподготовки врачей</p><p> 630091,  г. Новосибирск, Красный пр-т, д. 52</p></bio><bio xml:lang="en"><p>52 Krasny Ave., Novosibirsk,  630091</p><p>3 Vertkovskaya Str., Novosibirsk,  630048</p></bio><email xlink:type="simple">ovpilipenko123@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лиханов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Likhanov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лиханов Андрей Владимирович  — д. м. н., профессор кафедры педиатрии факультета повышения квалификации и профессиональной переподготовки врачей</p><p>630091,  г. Новосибирск, Красный пр-т, д. 52</p></bio><bio xml:lang="en"><p>52 Krasny Ave., Novosibirsk,  630091</p></bio><email xlink:type="simple">avlikhanov@ngs.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Новосибирский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Городской центр эндокринных и обменных нарушений ГБУЗ НСО «Детская городская клиническая больница № 1»;ФГБОУ ВО «Новосибирский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Novosibirsk State Medical University; City Center for Endocrine and Metabolic Disorders of the Children's City Clinical Hospital No. 1</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>20</day><month>02</month><year>2025</year></pub-date><volume>22</volume><issue>7</issue><issue-title>ПЕДИАТРИЯ</issue-title><fpage>24</fpage><lpage>30</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Коваренко М.А., Кондюрина Е.Г., Зеленская В.В., Анохина Т.Ю., Пилипенко О.В., Лиханов А.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Коваренко М.А., Кондюрина Е.Г., Зеленская В.В., Анохина Т.Ю., Пилипенко О.В., Лиханов А.В.</copyright-holder><copyright-holder xml:lang="en">Kovarenko M.A., Kondyurina E.G., Zelenskaia V.V., Anokhina T.Y., Pilipenko O.V., Likhanov A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://docru.elpub.ru/jour/article/view/299">https://docru.elpub.ru/jour/article/view/299</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования. Проанализировать распространенность ожирения у детей и подростков Новосибирской области за период 2018–2022 гг., оценить состояние липидного и углеводного обмена у детей с первичным ожирением 1–2-й степени без артериальной гипертензии.</p></sec><sec><title>Дизайн</title><p>Дизайн. Наблюдательное описательное поперечное исследование.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведен анализ статистических показателей по данным годовых отчетных форм федерального статистического наблюдения № 12 у детей и подростков Новосибирской области и базы данных пациентов Городского центра эндокринных и обменных нарушений в ГБУЗ НО «Детская городская клиническая больница № 1» за 2018–2022 гг. Обследованы также 154 ребенка в возрасте 6–17 лет с первичным ожирением 1–2-й степени, без артериальной гипертензии в анамнезе и на момент осмотра, у них исследованы стандартный липидный профиль, показатели глюкозы крови натощак, инсулина, перорального глюкозотолерантного теста, индекса Homeostasis Model Assessment (HOMA) и триглицерид-глюкозного индекса (Triglyceride and Glucose Index, TyG).Результаты. По данным отчетной формы № 12, в Новосибирской области в 2018–2022 гг. ожирение лидирует среди заболеваний эндокринной системы у детей и подростков. Максимальное число случаев ожирения зарегистрировано в 2019 г. (9030 чел.; 1560,7 случая на 100 тыс. населения), минимальное — в 2021 г. (7289 чел.; 1235,6 случая на 100 тыс. населения). Среди обследованных детей с первичным ожирением 1–2-й степени нарушенная толерантность к глюкозе выявлена у 5,2%, изменения стандартного липидного профиля — у 33,8%. Детей с инсулинорезистентностью, определенной по индексу НОМА выше 3,16, было 46 (29,9%), по индексу ТyG выше 7,98 — 78 (50,6%).</p></sec><sec><title>Заключение</title><p>Заключение. По данным статистической отчетности, наиболее часто ожирение встречается у подростков 15–17 лет. Нарастание как абсолютного, так и относительного количества случаев ожирения с возрастом требует более раннего начала реализации программ профилактики избыточной массы тела для снижения заболеваемости и коморбидности. Выявленная высокая коморбидность по основным компонентам метаболического синдрома у пациентов с 1–2-й степенью ожирения указывает на необходимость раннего обследования, коррекции и мониторинга ключевых кардиометаболических факторов риска в этой группе детей</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Aim</title><p>Aim. To analyze the obesity prevalence in children and adolescents of the Novosibirsk region for the period 2018–2022, to assess the state of lipid and carbohydrate metabolism in children with primary obesity of 1–2 degrees without arterial hypertension.</p></sec><sec><title>Design</title><p>Design. An observational, descriptive, cross-sectional study.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. The analysis of statistical indicators according to the annual reporting forms of federal statistical observation No. 12 in children and adolescents of the Novosibirsk Region and the patient database of the City Center for Endocrine and Metabolic Disorders in the Children's City Clinical Hospital No. 1 of the Novosibirsk Region for 2018–2022 was carried out. We also examined 154 children aged 6–17 years with primary obesity of 1–2 degrees, without arterial hypertension in medical history and at the time of examination; their standard lipid profile, fasting blood glucose, insulin, oral glucose tolerance test, Homeostasis Model Assessment (HOMA) and Triglyceride[<xref ref-type="bibr" rid="cit1">1</xref>]Glucose Index (TyG) were examined.</p></sec><sec><title>Results</title><p>Results. According to the data of report form No. 12 in the Novosibirsk Region for 2018–2022, obesity is the leader among the endocrine system diseases in children and adolescents. The maximum number of cases of obesity among children and adolescents was registered in 2019 (9030 people; 1560.7 cases per 100 thousand population), the minimum — in 2021 (7289 people; 1235.6 cases per 100 thousand population). Among the examined children with primary obesity of 1–2 degrees, impaired glucose tolerance was detected in 5.2%, changes in the standard lipid profile — in 33.8%. The group of children with insulin resistance estimated by the HOMA index above 3.16 was 46 people (29.9%), according to the TyG index — above 7.98 — 78 children (50.6%).</p></sec><sec><title>Conclusions</title><p>Conclusions. According to statistical reporting, the maximum number of cases of obesity among children and adolescents was registered in 2019, the minimum — in 2021, the incidence rate is lower than the prevalence of pathology in Russia. The highest prevalence of obesity was noted in the age group of 15–17 years. The revealed high comorbidity for the main components of the metabolic syndrome in patients with 1–2 degrees of obesity indicates the need for early examination, correction and monitoring of key cardiometabolic risk factors in this patients group.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>распространенность ожирения</kwd><kwd>дети</kwd><kwd>липидный и углеводный обмен</kwd><kwd>дислипидемия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>prevalence of obesity</kwd><kwd>children</kwd><kwd>lipid and carbohydrate metabolism</kwd><kwd>dyslipidemia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Голубев Н.А., Огрызко Е.В., Шелепова Е.А., Залевская О.В. Заболеваемость детей болезнями эндокринной системы, расстройствами питания и нарушениями обмена веществ в рамках национального проекта «Здравоохранение» Российской Федерации. 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