<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">docru</journal-id><journal-title-group><journal-title xml:lang="ru">Доктор.Ру</journal-title><trans-title-group xml:lang="en"><trans-title>Title</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-2378</issn><issn pub-type="epub">2713-2994</issn><publisher><publisher-name>ООО "ГК "РУСМЕДИКАЛ"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31550/1727-2378-2022-21-8-6-11</article-id><article-id custom-type="elpub" pub-id-type="custom">docru-25</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕВРОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>NEUROLOGY</subject></subj-group></article-categories><title-group><article-title>Использование транскраниальной микрополяризации у пациентов с сочетанием двигательных и речевых нарушений при инсульте</article-title><trans-title-group xml:lang="en"><trans-title>Use of Transcranial Direct Current Stimulation in Post-stroke Patients with Motor and Speech Disturbances</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5053-3305</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гасанбекова</surname><given-names>А. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Gasanbekova</surname><given-names>A. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гасанбекова Алина Рустамовна — аспирант кафедры неврологии и нейрохирургии</p><p>153012, г. Иваново, Шереметьевский просп., д. 8</p></bio><bio xml:lang="en"><p>8 Sheremetevsky Prospect, Ivanovo, 153012</p></bio><email xlink:type="simple">iv.veronika37@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3429-9640</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ястребцева</surname><given-names>И. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Yastrebtseva</surname><given-names>I. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ястребцева Ирина Петровна — д. м. н., доцент, профессор кафедры неврологии и нейрохирургии</p><p>153012, Иваново, Шереметьевский просп., д. 8</p></bio><bio xml:lang="en"><p>8 Sheremetevsky Prospect, Ivanovo, 153012</p></bio><email xlink:type="simple">ip.2007@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3249-1620</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дмитриев</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dmitriev</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитриев Евгений Вячеславович — врач-физиотерапевт Клиники</p><p>153012, г. Иваново, Шереметьевский просп., д. 8</p></bio><bio xml:lang="en"><p>8 Sheremetevsky Prospect, Ivanovo, 153012</p></bio><email xlink:type="simple">ew.dmitriew2014@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8044-2121</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бочкова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bochkova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бочкова Елена Александровна — к. м. н., врач-невролог Клиники</p><p>153012, г. Иваново, Шереметьевский просп., д. 8</p></bio><bio xml:lang="en"><p>8 Sheremetevsky Prospect, Ivanovo, 153012</p></bio><email xlink:type="simple">bochkova_70@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Ивановская государственная медицинская академия» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Ivanovo State Medical Academy (a Federal Governmentfunded Educational Institution of Higher Education), Russian Federation Ministry of Health</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>13</day><month>02</month><year>2025</year></pub-date><volume>21</volume><issue>8</issue><issue-title>НЕВРОЛОГИЯ. ПСИХИАТРИЯ</issue-title><fpage>6</fpage><lpage>11</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гасанбекова А.Р., Ястребцева И.П., Дмитриев Е.В., Бочкова Е.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Гасанбекова А.Р., Ястребцева И.П., Дмитриев Е.В., Бочкова Е.А.</copyright-holder><copyright-holder xml:lang="en">Gasanbekova A.R., Yastrebtseva I.P., Dmitriev E.V., Bochkova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://docru.elpub.ru/jour/article/view/25">https://docru.elpub.ru/jour/article/view/25</self-uri><abstract><sec><title>Цель исследования</title><p>Цель исследования: оценить эффективность транскраниальной микрополяризации (ТКМП) в комплексе реабилитационных мероприятий у пациентов, перенесших ишемический инсульт, с сочетанием двигательных и речевых нарушений.</p></sec><sec><title>Дизайн</title><p>Дизайн: проспективное исследование.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Проведено тестирование 77 пациентов в раннем восстановительном периоде ишемического инсульта по Монреальской шкале когнитивной оценки, Госпитальной шкале тревоги и депрессии, Шкале Вассермана, Тесту оценки дизартрии, Шкале восстановления локуса-контроля, Шкале комитета медицинских исследований, Тесту Френчай.</p></sec><sec><title>Результаты</title><p>Результаты. Сила мышц дистальных отделов парализованной верхней конечности возросла у больных с применением ТКМП на двигательные зоны (p &lt; 0,05). По тесту Френчай показатели в ходе реабилитации улучшились во всех группах исследования (p &lt; 0,05). Результаты по субшкале «внимание» Монреальской шкалы когнитивной оценки, Госпитальной шкале тревоги и депрессии и Шкале восстановления локуса контроля статистически значимо повышались у пациентов при воздействии ТКМП на речевые зоны.</p></sec><sec><title>Заключение</title><p>Заключение. Применение ТКМП у пациентов с инсультом улучшает когнитивные функции по называнию предметов, осуществлению речевых функций, что сопровождается возрастанием мотивации больных на реабилитацию и лечение и отражается на повышении качества их жизни. Использование ТКМП на двигательные зоны способствует улучшению моторных функций и повышает двигательные возможности больных инсультом. При наложении электродов на речевые зоны отмечается уменьшение тревоги, депрессии и улучшение внимания.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Study Objective</title><p>Study Objective: To assess the efficiency of transcranial direct current stimulation (tDCS) as a component of rehabilitation measures in ischemic stroke patients with motor and speech disturbances.</p></sec><sec><title>Study Design</title><p>Study Design: prospective study.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods. We tested 77 patients in the early rehabilitation period after ischemic stroke using Montreal Cognitive Assessment, Hospital Anxiety and Depression Scale, Wassermann Scale, Dysarthria Assessment Scale, Locus of Control Recovery Assessment Scale, Medical Research Committee Scale, Franchay Scale.</p></sec><sec><title>Study Results</title><p>Study Results. Distal muscle strength in paralytic upper extremity improved in patients who were treated with motor zone tDCS (p &lt; 0.05). Franchay Scale results during rehabilitation demonstrated improvements in all study groups (p &lt; 0.05). “Attention” sub-scale results in Montreal Cognitive Assessment, Hospital Anxiety and Depression Scale, and Locus of Control Recovery Assessment Scale were statistically higher in patients who were treated with speech zone tDCS.</p></sec><sec><title>Conclusion</title><p>Conclusion. Use of tDCS in stroke patients improves cognitive functions in naming objects, speech functions, and patients’ motivation to rehabilitation grows, positively impacting their quality of life. Use of tDCS in motor zones facilitates motor function improvement and enhances dexterity of stroke patients. When electrodes were used in speech zones, anxiety and depression reduced, while attention improved.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>транскраниальная микрополяризация</kwd><kwd>ишемический инсульт</kwd><kwd>двигательные нарушения</kwd><kwd>афазия</kwd><kwd>дизартрия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>transcranial direct current stimulation</kwd><kwd>ischemic stroke</kwd><kwd>motor disturbances</kwd><kwd>aphasia</kwd><kwd>dysarthria</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Иванова Г.Е., Белкин А.А., Беляев А.Ф. и др. Пилотный проект «развитие системы медицинской реабилитации в Российской Федерации». Система контроля и мониторирования эффективности медицинской реабилитации при острых нарушениях мозгового кровообращения. Вестник Ивановской медицинской академии. 2016; 21(1): 6–14.</mixed-citation><mixed-citation xml:lang="en">Ivanova G.E., Belkin A.A., Belyaev A.F. et al. Pilot project “Development of medical rehabilitation system in the Russian Federation”. Effectiveness of medical rehabilitation in acute disorders of cerebral circulation: control and monitoring system. Bulletin of the Ivanovo Medical Academy. 2016; 21(1): 6–14. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Elsner B., Kugler J., Pohl M., Mehrholz J. Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive functioning, in people after stroke (Review). Cochrane Database of Systematic Reviews. 2020; 11: CD009645. DOI: 10.1002/14651858.CD009645.pub4</mixed-citation><mixed-citation xml:lang="en">Elsner B., Kugler J., Pohl M., Mehrholz J. Transcranial direct current stimulation (tDCS) for improving activities of daily living, and physical and cognitive functioning, in people after stroke (Review). Cochrane Database of Systematic Reviews. 2020; 11: CD009645. DOI: 10.1002/14651858.CD009645.pub4</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Brunoni A.R., Amadera J., Berbel B. et al. A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation. Int. J. Neuropsychopharmacol. 2011; 14(8): 1133–1145. DOI: 10.1017/S1461145710001690</mixed-citation><mixed-citation xml:lang="en">Brunoni A.R., Amadera J., Berbel B. et al. A systematic review on reporting and assessment of adverse effects associated with transcranial direct current stimulation. Int. J. Neuropsychopharmacol. 2011; 14(8): 1133–1145. DOI: 10.1017/S1461145710001690</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Chhabraa H., Bosea A., Shivakumara V. et al. Tolerance of transcranial direct current stimulation in psychiatric disorders: An analysis of 2000+ sessions. Psychyatry Res. 2020; 28(4): 112744. DOI: 10.1016/j.psychres.2020.112744</mixed-citation><mixed-citation xml:lang="en">Chhabraa H., Bosea A., Shivakumara V. et al. Tolerance of transcranial direct current stimulation in psychiatric disorders: An analysis of 2000+ sessions. Psychyatry Res. 2020; 28(4): 112744. DOI: 10.1016/j.psychres.2020.112744</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Fridriksson J., Rorden C., Elm J. et al. Transcranial direct current stimulation vs sham stimulation to treat aphasia after stroke: a randomized clinical trial. JAMA Neurol. 2018; 75(12): 1470– 1476. DOI: 10.1001/jamaneurol.2018.2287</mixed-citation><mixed-citation xml:lang="en">Fridriksson J., Rorden C., Elm J. et al. Transcranial direct current stimulation vs sham stimulation to treat aphasia after stroke: a randomized clinical trial. JAMA Neurol. 2018; 75(12): 1470– 1476. DOI: 10.1001/jamaneurol.2018.2287</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Marangolo P., Fiori V., Sabatini U., Pasquale G. Bilateral transcranial direct current stimulation language treatment enhances functional connectivity in the left hemisphere: preliminary data from aphasia. Journal of cognitive neuroscience. 2016; 13: 724–738. DOI: 10.1162/jocn_a_00927</mixed-citation><mixed-citation xml:lang="en">Marangolo P., Fiori V., Sabatini U., Pasquale G. Bilateral transcranial direct current stimulation language treatment enhances functional connectivity in the left hemisphere: preliminary data from aphasia. Journal of cognitive neuroscience. 2016; 13: 724–738. DOI: 10.1162/jocn_a_00927</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Meinzer M., Darkow R., Lindenberg R., Flöel A. Electrical stimulation of the motor cortex enhances treatment outcome in post-stroke aphasia. Brain. 2016; 139(4): 1152–1163. DOI: 10.1093/brain/aww002</mixed-citation><mixed-citation xml:lang="en">Meinzer M., Darkow R., Lindenberg R., Flöel A. Electrical stimulation of the motor cortex enhances treatment outcome in post-stroke aphasia. Brain. 2016; 139(4): 1152–1163. DOI: 10.1093/brain/aww002</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Vila-Nova C., Lucena H.P., Lucena R. et al. Effect of anodal tDCS on articulatory accuracy, word production, and syllable repetition in subjects with aphasia: a Crossover, double-blinded, sham-controlled trial. Neurol. Ther. 2019; 8: 411–424. DOI: 10.1007/s40120-019-00149-4</mixed-citation><mixed-citation xml:lang="en">Vila-Nova C., Lucena H.P., Lucena R. et al. Effect of anodal tDCS on articulatory accuracy, word production, and syllable repetition in subjects with aphasia: a Crossover, double-blinded, sham-controlled trial. Neurol. Ther. 2019; 8: 411–424. DOI: 10.1007/s40120-019-00149-4</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Шелякин А.М., Преображенская И.Г., Тюлькин О.Н. Микрополяризация мозга: неинвазивный способ коррекции морфофункциональных нарушений при острых очаговых поражениях головного мозга и их последствиях. Журнал неврологии и психиатрии им. С. С. Корсакова. 2006; 106(10): 27–37.</mixed-citation><mixed-citation xml:lang="en">Shelyakin A.M., Preobrazhenskaya I.G. Tyul'kin O.N. Micropolarization of the brain: a noninvasive method for correction of morphological and functional disturbances in acute focal brain lesions and their consequences. Zh. Nevrol. Psikhiatr. Im. S.S. Korsakova. 2006; 106(10): 27–37. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Shaker H.A., Sawan S.A., Fahmy E.M., Ismail R.S. Effect of transcranial direct current stimulation on cognitive function in stroke patients. Egypt. J. Neurol., Psychiatr. Neurosurg. 2018; 6: 54(1): 32. DOI: 10.1186/s41983-018-0037-8</mixed-citation><mixed-citation xml:lang="en">Shaker H.A., Sawan S.A., Fahmy E.M., Ismail R.S. Effect of transcranial direct current stimulation on cognitive function in stroke patients. Egypt. J. Neurol., Psychiatr. Neurosurg. 2018; 6: 54(1): 32. DOI: 10.1186/s41983-018-0037-8</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">McClintock S.M., Martin D.M., Lisanby S.H. et al. Neurocognitive effects of transcranial direct current stimulation (tDCS) in unipolar and bipolar depression: findings from an international randomized controlled trial. Depress Anxiety. 2020; 37(3): 261–272. DOI: 10.1002/da.22988</mixed-citation><mixed-citation xml:lang="en">McClintock S.M., Martin D.M., Lisanby S.H. et al. Neurocognitive effects of transcranial direct current stimulation (tDCS) in unipolar and bipolar depression: findings from an international randomized controlled trial. Depress Anxiety. 2020; 37(3): 261–272. DOI: 10.1002/da.22988</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Alisar D.C., Ozen S., Sozay S. Effects of bihemispheric transcranial direct current stimulation on upper extremity function in stroke patients: a randomized double-blind sham-controlled study. J. Stroke. 2019; 29(1): 1044–1054. DOI: 10.1016/j.jstrokecerebrovasdis</mixed-citation><mixed-citation xml:lang="en">Alisar D.C., Ozen S., Sozay S. Effects of bihemispheric transcranial direct current stimulation on upper extremity function in stroke patients: a randomized double-blind sham-controlled study. J. Stroke. 2019; 29(1): 1044–1054. DOI: 10.1016/j.jstrokecerebrovasdis</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Pelletier S.J., Cicchetti F. Cellular and molecular mechanisms of action of transcranial direct current stimulation: Evidence from in vitro and in vivo models. Int. J. Neuropsychopharmacol. 2014; 18(2): 47. DOI: 10.1093/ijnp/pyu047</mixed-citation><mixed-citation xml:lang="en">Pelletier S.J., Cicchetti F. Cellular and molecular mechanisms of action of transcranial direct current stimulation: Evidence from in vitro and in vivo models. Int. J. Neuropsychopharmacol. 2014; 18(2): 47. DOI: 10.1093/ijnp/pyu047</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Yoon K.J., Oh B.M., Kim D.Y. Functional improvement and neuroplastic effects of anodal transcranial direct current stimulation (tDCS) delivered 1 day vs. 1 week after cerebral ischemia in rats. Brain Res. 2012; 1452: 61–72. DOI: 10.1016/j.brainres.2012.02.062</mixed-citation><mixed-citation xml:lang="en">Yoon K.J., Oh B.M., Kim D.Y. Functional improvement and neuroplastic effects of anodal transcranial direct current stimulation (tDCS) delivered 1 day vs. 1 week after cerebral ischemia in rats. Brain Res. 2012; 1452: 61–72. DOI: 10.1016/j.brainres.2012.02.062</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Fridriksson J., Elm J., Stark B.C. et al. BDNF genotype and tDCS interaction in aphasia treatment. Brain Stimul. 2018; 11(6): 1276– 1281. DOI: 10.1016/j.brs.2018.08.009</mixed-citation><mixed-citation xml:lang="en">Fridriksson J., Elm J., Stark B.C. et al. BDNF genotype and tDCS interaction in aphasia treatment. Brain Stimul. 2018; 11(6): 1276– 1281. DOI: 10.1016/j.brs.2018.08.009</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Guillouët E., Cogné M., Saverot E., Roche N. Impact of сombined transcranial direct current stimulation and speech-language therapy on spontaneous speech in aphasia: a randomized controlled doubleblind study. J. Int. Neuropsychol. Soc. 2020; 26(1): 7–18. DOI: 10.1017/S1355617719001036</mixed-citation><mixed-citation xml:lang="en">Guillouët E., Cogné M., Saverot E., Roche N. Impact of сombined transcranial direct current stimulation and speech-language therapy on spontaneous speech in aphasia: a randomized controlled doubleblind study. J. Int. Neuropsychol. Soc. 2020; 26(1): 7–18. DOI: 10.1017/S1355617719001036</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Wang J., Wu D., Cheng Y. et al. Effects of transcranial direct current stimulation on apraxia of speech and cortical activation in patients with stroke: a randomized sham-controlled study. Am. J. Speech Lang. Pathol. 2019; 28(4): 1625–1637. DOI: 10.1044/2019_AJSLP-19-0069</mixed-citation><mixed-citation xml:lang="en">Wang J., Wu D., Cheng Y. et al. Effects of transcranial direct current stimulation on apraxia of speech and cortical activation in patients with stroke: a randomized sham-controlled study. Am. J. Speech Lang. Pathol. 2019; 28(4): 1625–1637. DOI: 10.1044/2019_AJSLP-19-0069</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Лобанов А.А., Попова О.В. Внимание человека: психофизиологические аспекты в норме и при нарушении. Международный студенческий научный вестник. 2017; (1): 1–18.</mixed-citation><mixed-citation xml:lang="en">Lobanov A.A., Popova O.V. Human attention: psychophysiological aspects normally and at disturbance. International Student Scientific Bulletin. 2017; (1): 1–18. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Чупина В.Б., Попенко Н.В. Особенности мотивационной направленности внутренней картины болезни и уровня жизнестойкости у пациентов с острым нарушением мозгового кровообращения в реабилитационном периоде. Современные проблемы науки и образования. 2016; (6): 34.</mixed-citation><mixed-citation xml:lang="en">Chupina V.B., Popenko N.V. The features of motivational direction of internal picture of disease and the level of vitality of patients with acute violations of cerebral circulation during the rehabilitation period. Modern problems of science and education. 2016; (6): 34. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Doncker W.D., Ondobaka S., Kuppuswamy A. Effect of transcranial direct current stimulation on post-stroke fatigue. J. Neurol. 2021; 268(8): 2831–2842. DOI: 10.1007/s00415-021-10442-8</mixed-citation><mixed-citation xml:lang="en">Doncker W.D., Ondobaka S., Kuppuswamy A. Effect of transcranial direct current stimulation on post-stroke fatigue. J. Neurol. 2021; 268(8): 2831–2842. DOI: 10.1007/s00415-021-10442-8</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Allman C., Amadi U., Anderson M.W. et al. Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke. Science Translational Medicine. 2016; 8(330): 330re1. DOI: 10.1126/scitranslmed.aad565</mixed-citation><mixed-citation xml:lang="en">Allman C., Amadi U., Anderson M.W. et al. Ipsilesional anodal tDCS enhances the functional benefits of rehabilitation in patients after stroke. Science Translational Medicine. 2016; 8(330): 330re1. DOI: 10.1126/scitranslmed.aad565</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Halakoo S., Ehsani F., Hosnian M. et al. The comparative effects of unilateral and bilateral transcranial direct current stimulation on motor learning and motor performance: A systematic review of literature and meta-analysis. J. Clin. Neurosci. 2020; 72: 8–14. DOI: 10.1016/j.jocn.2019.12.022</mixed-citation><mixed-citation xml:lang="en">Halakoo S., Ehsani F., Hosnian M. et al. The comparative effects of unilateral and bilateral transcranial direct current stimulation on motor learning and motor performance: A systematic review of literature and meta-analysis. J. Clin. Neurosci. 2020; 72: 8–14. DOI: 10.1016/j.jocn.2019.12.022</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Koh C.L., Lin J.H., Jeng J.S. et al. Effects of transcranial direct current stimulation with sensory modulation on stroke motor rehabilitation: a randomized controlled trial. Arch. Phys. Med. Rehab. 2017; 98(12): 2477–2484. DOI: 10.1016/j.apmr.2017.05.025</mixed-citation><mixed-citation xml:lang="en">Koh C.L., Lin J.H., Jeng J.S. et al. Effects of transcranial direct current stimulation with sensory modulation on stroke motor rehabilitation: a randomized controlled trial. Arch. Phys. Med. Rehab. 2017; 98(12): 2477–2484. DOI: 10.1016/j.apmr.2017.05.025</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Marquez J.L., Conley A.C., Karayanidis F. et al. Determining the benefits of transcranial direct current stimulation on functional upper limb movement in chronic stroke. Int. J. Rehab. Res. 2017; 40(2): 138–145. DOI: 10.1097/MRR.0000000000000220</mixed-citation><mixed-citation xml:lang="en">Marquez J.L., Conley A.C., Karayanidis F. et al. Determining the benefits of transcranial direct current stimulation on functional upper limb movement in chronic stroke. Int. J. Rehab. Res. 2017; 40(2): 138–145. DOI: 10.1097/MRR.0000000000000220</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Fregni F., El-Hagrassy M.M., Pacheco-Barrios K. et al. Evidence-based guidelines and secondary meta-analysis for the use of transcranial direct current stimulation in neurological and psychiatric disorders. Int. J. Neuropsychopharmacol. 2021; 24(4): 256–313. DOI: 10.1093/ijnp/pyaa051</mixed-citation><mixed-citation xml:lang="en">Fregni F., El-Hagrassy M.M., Pacheco-Barrios K. et al. Evidence-based guidelines and secondary meta-analysis for the use of transcranial direct current stimulation in neurological and psychiatric disorders. Int. J. Neuropsychopharmacol. 2021; 24(4): 256–313. DOI: 10.1093/ijnp/pyaa051</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Каркищенко Н.Н. (ред.) Применение комплексной медицинской технологии нейромодуляции, методические рекомендации ФМБА России. M.; 2017. 65 c.</mixed-citation><mixed-citation xml:lang="en">Karkishhenko N.N. (ed.) The use of complex medical technology of neuromodulation, methodological recommendations of the Federal Medical and Biological Agency of Russia. Moscow; 2017. 65 p. (in Russian)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
