<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">docru</journal-id><journal-title-group><journal-title xml:lang="ru">Доктор.Ру</journal-title><trans-title-group xml:lang="en"><trans-title>Title</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-2378</issn><issn pub-type="epub">2713-2994</issn><publisher><publisher-name>ООО "ГК "РУСМЕДИКАЛ"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31550/1727-2378-2023-22-2-70-75</article-id><article-id custom-type="elpub" pub-id-type="custom">docru-239</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПУЛЬМОНОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PULMONOLOGY</subject></subj-group></article-categories><title-group><article-title>Респираторная реабилитация пациентов с COVID-19: текущее состояние проблемы</article-title><trans-title-group xml:lang="en"><trans-title>Respiratory Rehabilitation of COVID-19 Patients: Current State of the Problem</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6116-1292</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>К. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>K. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петров Кирилл Владимирович — аспирант кафедры физической и реабилитационной медицины с курсом ПО ФГБОУ ВО КрасГМУ им. проф. В.Ф. Войно-Ясенецкого Минздрава России.</p><p>660022, Красноярск, ул. Партизана Железняка, д. 1</p></bio><bio xml:lang="en"><p>1 Partizan Zheleznyak St., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">kllpetrov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9412-1529</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Можейко</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Mozheyko</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Можейко Елена Юрьевна — д. м. н., доцент, заведующая кафедрой физической и реабилитационной медицины с курсом ПО ФГБОУ ВО КрасГМУ им. проф. В.Ф. Войно-Ясенецкого Минздрава России.</p><p>660022, Красноярск, ул. Партизана Железняка, д. 1</p></bio><bio xml:lang="en"><p>1 Partizan Zheleznyak St., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">el_mozhejko@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2757-4875</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петров Артём Владимирович — студент 4-го курса лечебного факультета ФГБОУ ВО КрасГМУ им. проф. В.Ф. Войно-Ясенецкого Минздрава России.</p><p>660022, Красноярск, ул. Партизана Железняка, д. 1</p></bio><bio xml:lang="en"><p>1 Partizan Zheleznyak St., Krasnoyarsk, 660022</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8982-5292</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демко</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Demko</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Демко Ирина Владимировна — д. м. н., профессор, заведующая кафедрой госпитальной терапии и иммунологии с курсом ПО ФГБОУ ВО КрасГМУ им. проф. В.Ф. Войно-Ясенецкого Минздрава России.</p><p>660022, Красноярск, ул. Партизана Железняка, д. 1</p></bio><bio xml:lang="en"><p>1 Partizan Zheleznyak St., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">demko64@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>18</day><month>02</month><year>2025</year></pub-date><volume>22</volume><issue>2</issue><issue-title>ТЕРАПИЯ</issue-title><fpage>70</fpage><lpage>75</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Петров К.В., Можейко Е.Ю., Петров А.В., Демко И.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Петров К.В., Можейко Е.Ю., Петров А.В., Демко И.В.</copyright-holder><copyright-holder xml:lang="en">Petrov K.V., Mozheyko E.Y., Petrov A.V., Demko I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://docru.elpub.ru/jour/article/view/239">https://docru.elpub.ru/jour/article/view/239</self-uri><abstract><sec><title>Цель</title><p>Цель: обобщить данные литературы по респираторной реабилитации у пациентов с новой коронавирусной инфекцией, оценить текущее состояние проблемы и перспективы ее решения.</p></sec><sec><title>Основные положения</title><p>Основные положения. Новая коронавирусная инфекция (COVID-19) — это высококонтагиозное острое респираторное инфекционное заболевание с первичным поражением верхних и нижних дыхательных путей, органов и систем организма человека. Проявления заболевания широко варьируются от бессимптомного носительства до клинически тяжелой формы вирусной пневмонии, требующей кислородной терапии и респираторной поддержки. Респираторная реабилитация играет жизненно важную роль в выздоровлении пациентов. В мире идет накопление базы данных и профессиональной информации о респираторной реабилитации пациентов с COVID-19, т.к. общепринятые методы реабилитации после респираторных заболеваний могут быть неэффективными или небезопасными.</p></sec><sec><title>Заключение</title><p>Заключение. Респираторную реабилитацию следует проводить на протяжении всего процесса лечения COVID-19, начиная в условиях отделений реанимации и интенсивной терапии при стабильном состоянии пациента. Реабилитационные мероприятия должны быть персонализированными. Будущие исследования должны помочь понять траекторию движения развития легочной реабилитации с целью улучшения качества жизни пациентов и скорейшего восстановления их активности.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective of the Review</title><p>Objective of the Review: To summarise the data from literature sources on respiratory rehabilitation of patients with the novel coronavirus infection; to assess the current state and perspectives.</p></sec><sec><title>Key Points</title><p>Key Points. The novel coronavirus infection (COVID-19) is a highly contagious acute respiratory disease with primary involvement of upper and lower respiratory tract, organs and systems of the body. The symptoms of the disease vary from asymptomatic carrier to clinically severe viral pneumonia that requires oxygen therapy and respiratory support. Respiratory rehabilitation is vital for patient recovery. Globally, there is more and more professional information and databases on respiratory rehabilitation of COVID-19 patients, since the common methods of rehabilitation after a respiratory disease can be ineffective or unsafe.</p></sec><sec><title>Conclusion</title><p>Conclusion. Respiratory rehabilitation should be an integral part of COVID-19 therapy, starting from ICU once the patient’s condition has stabilised. Rehabilitation should be personalised. Future studies will help in understanding the development path of pulmonary rehabilitation in order to improve the quality of patients’ life and to facilitate faster activity restoration.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>реабилитация</kwd><kwd>респираторная реабилитация</kwd><kwd>коронавирусная инфекция</kwd><kwd>COVID-19</kwd><kwd>дыхательные упражнения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rehabilitation</kwd><kwd>respiratory rehabilitation</kwd><kwd>coronavirus infection</kwd><kwd>COVID-19</kwd><kwd>breathing exercises</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Brugliera L., Spina A., Castellazzi P. et al. Rehabilitation of COVID-19 patients. J. Rehabil. Med. 2020;52(4):jrm00046. DOI: 10.2340/16501977-2678</mixed-citation><mixed-citation xml:lang="en">Brugliera L., Spina A., Castellazzi P. et al. Rehabilitation of COVID-19 patients. J. Rehabil. Med. 2020;52(4):jrm00046. DOI: 10.2340/16501977-2678</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Бубнова М.Г., Шляхто Е.В., Аронов Д.М. и др. Новая коронавирусная инфекционная болезнь COVID-19: особенности комплексной кардиологической и респираторной реабилитации. Российский кардиологический журнал. 2021;26(5):4487. DOI: 10.15829/1560-4071-2021-4487</mixed-citation><mixed-citation xml:lang="en">Bubnova M.G., Shlyakhto E.V., Aronov D.M. et al. Coronavirus disease 2019: features of comprehensive cardiac and pulmonary rehabilitation. Russian Journal of Cardiology. 2021;26(5):4487. (in Russian). DOI: 10.15829/1560-4071-2021-4487</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Кабыш С.С., Карпенкова А.Д., Прокопенко С.В. Когнитивные нарушения и COVID-19. Сибирское медицинское обозрение. 2022;(2):40–48. DOI: 10.20333/25000136-2022-2-40-48</mixed-citation><mixed-citation xml:lang="en">Kabysh S.S., Karpenkova A.D., Prokopenko S.V. Cognitive impairments and COVID-19. Siberian Medical Review. 2022;(2):40–48. (in Russian). DOI: 10.20333/25000136-2022-2-40-48</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Ма-Ван-дэ В.Д., Зайцев Д.Н., Филев А.П. и др. Клинико-лабораторные маркеры тяжести течения новой коронавирусной инфекции (COVID-19). Сибирское медицинское обозрение. 2022;(3):40–48. DOI: 10.20333/25000136-2022-3-40-48</mixed-citation><mixed-citation xml:lang="en">Ma-Van-de V.D., Zaitsev D.N., Filev A.P. et al. Clinical and laboratory markers of severity of the new coronavirus infection (COVID-19). Siberian Medical Review. 2022;(3):40–48. (in Russian). DOI: 10.20333/25000136-2022-3-40-48</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Forchette L., Sebastian W., Liu T. A Comprehensive review of COVID-19 virology, vaccines, variants, and therapeutics. Curr. Med. Sci. 2021;41(6):1037–1051. DOI: 10.1007/s11596-021-2395-1</mixed-citation><mixed-citation xml:lang="en">Forchette L., Sebastian W., Liu T. A Comprehensive review of COVID-19 virology, vaccines, variants, and therapeutics. Curr. Med. Sci. 2021;41(6):1037–1051. DOI: 10.1007/s11596-021-2395-1</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Davies N.G., Abbott S., Barnard R.C. et al. Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England. Science. 2021;372(6538):eabg3055. DOI: 10.1126/science.abg3055</mixed-citation><mixed-citation xml:lang="en">Davies N.G., Abbott S., Barnard R.C. et al. Estimated transmissibility and impact of SARS-CoV-2 lineage B.1.1.7 in England. Science. 2021;372(6538):eabg3055. DOI: 10.1126/science.abg3055</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Leung K., Shum M.H., Leung G.M. et al. Early transmissibility assessment of the n501y mutant strains of sars-cov-2 in the United Kingdom, October to November 2020. EuroSurveill.2021;26:2002106. DOI: 10.2807/1560-7917.ES.2020.26.1.2002106</mixed-citation><mixed-citation xml:lang="en">Leung K., Shum M.H., Leung G.M. et al. Early transmissibility assessment of the n501y mutant strains of sars-cov-2 in the United Kingdom, October to November 2020. EuroSurveill.2021;26:2002106. DOI: 10.2807/1560-7917.ES.2020.26.1.2002106</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Volz E., Mishra S., Chand M. et al. Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature. 2021;593(7858):266–269. DOI: 10.1038/s41586-021-03470-x</mixed-citation><mixed-citation xml:lang="en">Volz E., Mishra S., Chand M. et al. Assessing transmissibility of SARS-CoV-2 lineage B.1.1.7 in England. Nature. 2021;593(7858):266–269. DOI: 10.1038/s41586-021-03470-x</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Public-Health-England. Investigation of novel SARS-CoV-2 variants of concern. (2021). URL: https://www.gov.uk/government/publications/investigation-of-novel-sars-cov-2-variant-variant-of-concern-20201201</mixed-citation><mixed-citation xml:lang="en">Public-Health-England. Investigation of novel SARS-CoV-2 variants of concern. (2021). URL: https://www.gov.uk/government/publications/investigation-of-novel-sars-cov-2-variant-variant-of-concern-20201201</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Pearson C.A.B., Russell T.W., Davies N., Kucharski A.J. Estimates of severity and transmissibility of novel South Africa SARS-CoV-2 Variant 501Y.V2 (2021). URL: https://cmmidgithubio/topics/covid19/sa-novel-variant.html</mixed-citation><mixed-citation xml:lang="en">Pearson C.A.B., Russell T.W., Davies N., Kucharski A.J. Estimates of severity and transmissibility of novel South Africa SARS-CoV-2 Variant 501Y.V2 (2021). URL: https://cmmidgithubio/topics/covid19/sa-novel-variant.html</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Volz E., Hill V., McCrone J.T., Price A. et. al. Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity. Cell. 2021;184(1):64–75.e11. DOI: 10.1016/j.cell.2020.11.020</mixed-citation><mixed-citation xml:lang="en">Volz E., Hill V., McCrone J.T., Price A. et. al. Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity. Cell. 2021;184(1):64–75.e11. DOI: 10.1016/j.cell.2020.11.020</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Wang P., Casner R.G., Nair M.S. et al. Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization. bioRxiv [Preprint]. 2021: 2021.03.01.433466. DOI: 10.1101/2021.03.01.433466</mixed-citation><mixed-citation xml:lang="en">Wang P., Casner R.G., Nair M.S. et al. Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization. bioRxiv [Preprint]. 2021: 2021.03.01.433466. DOI: 10.1101/2021.03.01.433466</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Campbell F., Archer B., Laurenson-Schafer H. et al. Increased transmissibility and global spread of SARS-CoV-2 variants of concern as at June 2021. Euro Surveill. 2021;26(24):2100509. DOI: 10.2807/1560-7917.ES.2021.26.24.2100509</mixed-citation><mixed-citation xml:lang="en">Campbell F., Archer B., Laurenson-Schafer H. et al. Increased transmissibility and global spread of SARS-CoV-2 variants of concern as at June 2021. Euro Surveill. 2021;26(24):2100509. DOI: 10.2807/1560-7917.ES.2021.26.24.2100509</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">SARS-CoV-2 Variants of concern and variants under investigation in England (2021). URL: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1001358/Variants_of_Concern_VOC_Technical_Briefing_18.pdf</mixed-citation><mixed-citation xml:lang="en">SARS-CoV-2 Variants of concern and variants under investigation in England (2021). URL: https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1001358/Variants_of_Concern_VOC_Technical_Briefing_18.pdf</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Sheikh A., McMenamin J., Taylor B., Robertson C. SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness. Lancet. 2021;397(10293):2461–2462. DOI: 10.1016/S0140-6736(21)01358-1</mixed-citation><mixed-citation xml:lang="en">Sheikh A., McMenamin J., Taylor B., Robertson C. SARS-CoV-2 Delta VOC in Scotland: demographics, risk of hospital admission, and vaccine effectiveness. Lancet. 2021;397(10293):2461–2462. DOI: 10.1016/S0140-6736(21)01358-1</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Khedar R.S., Mittal K., Ambaliya H.C. et al. Greater COVID-19 severity and mortality in hospitalized patients in second (Delta Variant) wave compared to the first: single centre prospective study in India. medRxiv. 2021; 2021.09.03.21263091. DOI: 10.1101/2021.09.03.21263091</mixed-citation><mixed-citation xml:lang="en">Khedar R.S., Mittal K., Ambaliya H.C. et al. Greater COVID-19 severity and mortality in hospitalized patients in second (Delta Variant) wave compared to the first: single centre prospective study in India. medRxiv. 2021; 2021.09.03.21263091. DOI: 10.1101/2021.09.03.21263091</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Sheikhzadegan S., Alaghemand N., Fox M., Venkataraman V. Analysis of the delta variant B.1.617.2 COVID-19. Clin. Pract. 2021;11(4):778–784. DOI: 10.3390/clinpract11040093</mixed-citation><mixed-citation xml:lang="en">Sheikhzadegan S., Alaghemand N., Fox M., Venkataraman V. Analysis of the delta variant B.1.617.2 COVID-19. Clin. Pract. 2021;11(4):778–784. DOI: 10.3390/clinpract11040093</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Araf Y., Akter F., Tang Y.D. et al. Omicron variant of SARS-CoV-2: Genomics, transmissibility, and responses to current COVID-19 vaccines. J. Med. Virol. 2022;94(5):1825–1832. DOI: 10.1002/jmv.27588/</mixed-citation><mixed-citation xml:lang="en">Araf Y., Akter F., Tang Y.D. et al. Omicron variant of SARS-CoV-2: Genomics, transmissibility, and responses to current COVID-19 vaccines. J. Med. Virol. 2022;94(5):1825–1832. DOI: 10.1002/jmv.27588/</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Vaporidi K., Akoumianaki E., Telias I. et al. Respiratory drive in critically ill patients. Pathophysiology and clinical implications. Am. J. Respir. Crit. Care Med. 2020;201(1):20–32. DOI: 10.1164/rccm.201903-0596SO</mixed-citation><mixed-citation xml:lang="en">Vaporidi K., Akoumianaki E., Telias I. et al. Respiratory drive in critically ill patients. Pathophysiology and clinical implications. Am. J. Respir. Crit. Care Med. 2020;201(1):20–32. DOI: 10.1164/rccm.201903-0596SO</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Manning H.L., Schwartzstein R.M. Pathophysiology of dyspnea. N. Engl. J. Med. 1995;333(23):1547–1553. DOI: 10.1056/NEJM199512073332307</mixed-citation><mixed-citation xml:lang="en">Manning H.L., Schwartzstein R.M. Pathophysiology of dyspnea. N. Engl. J. Med. 1995;333(23):1547–1553. DOI: 10.1056/NEJM199512073332307</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Torres-Torrelo H., Ortega-Sáenz P., Gao L., López-Barneo J. Lactate sensing mechanisms in arterial chemoreceptor cells. Nat. Commun. 2021;12(1):4166. DOI: 10.1038/s41467-021-24444-7</mixed-citation><mixed-citation xml:lang="en">Torres-Torrelo H., Ortega-Sáenz P., Gao L., López-Barneo J. Lactate sensing mechanisms in arterial chemoreceptor cells. Nat. Commun. 2021;12(1):4166. DOI: 10.1038/s41467-021-24444-7</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Dhont S., Derom E., Van Braeckel E. et al. The pathophysiology of 'happy' hypoxemia in COVID-19. Respir. Res. 2020;21(1):198. DOI: 10.1186/s12931-020-01462-5</mixed-citation><mixed-citation xml:lang="en">Dhont S., Derom E., Van Braeckel E. et al. The pathophysiology of 'happy' hypoxemia in COVID-19. Respir. Res. 2020;21(1):198. DOI: 10.1186/s12931-020-01462-5</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Lippi G., Henry B.M. Chronic obstructive pulmonary disease is associated with severe coronavirus disease 2019 (COVID-19). Respir. Med. 2020;167:105941. DOI: 10.1016/j.rmed.2020.105941</mixed-citation><mixed-citation xml:lang="en">Lippi G., Henry B.M. Chronic obstructive pulmonary disease is associated with severe coronavirus disease 2019 (COVID-19). Respir. Med. 2020;167:105941. DOI: 10.1016/j.rmed.2020.105941</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Pericàs J.M., Hernandez-Meneses M., Sheahan T.P. et al. COVID-19: from epidemiology to treatment. Eur. Heart J. 2020;41(22):2092–2112. DOI: 10.1093/eurheartj/ehaa462</mixed-citation><mixed-citation xml:lang="en">Pericàs J.M., Hernandez-Meneses M., Sheahan T.P. et al. COVID-19: from epidemiology to treatment. Eur. Heart J. 2020;41(22):2092–2112. DOI: 10.1093/eurheartj/ehaa462</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Wu C., Chen X., Cai Y. et al. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern. Med. 2020;180(7):934–943. DOI: 10.1001/jamainternmed.2020.0994</mixed-citation><mixed-citation xml:lang="en">Wu C., Chen X., Cai Y. et al. Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China. JAMA Intern. Med. 2020;180(7):934–943. DOI: 10.1001/jamainternmed.2020.0994</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Parohan M., Yaghoubi S., Seraji A. et al. Risk factors for mortality in patients with Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies. Aging Male. 2020;23(5):1416–1424. DOI: 10.1080/13685538.2020.1774748</mixed-citation><mixed-citation xml:lang="en">Parohan M., Yaghoubi S., Seraji A. et al. Risk factors for mortality in patients with Coronavirus disease 2019 (COVID-19) infection: a systematic review and meta-analysis of observational studies. Aging Male. 2020;23(5):1416–1424. DOI: 10.1080/13685538.2020.1774748</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Временные методические рекомендации «Профилактика, диагностика и лечение новой коронавирусной инфекции (COVID-19). Версия 6 (28.04.2020)». 18 c. URL: https://static1.rosminzdrav.ru/system/attachments/attaches/000/050/122/original/28042020_%D0%9CR_COVID-19_v6.pdf</mixed-citation><mixed-citation xml:lang="en">Interim guidelines “Prevention, diagnosis and treatment of a new coronavirus infection (COVID-19). Version 6 (28.04.2020)». 18 p. (in Russian). URL: https://static1.rosminzdrav.ru/system/attachments/attaches/000/050/122/original/28042020_%D0%9CR_COVID-19_v6.pdf</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Siddiq M.A.B., Rathore F.A., Clegg D., Rasker J.J. Pulmonary rehabilitation in COVID-19 patients: a scoping review of current practice and its application during the pandemic. Turk. J. Phys. Med. Rehabil. 2020;66(4):480–494. DOI: 10.5606/tftrd.2020.6889</mixed-citation><mixed-citation xml:lang="en">Siddiq M.A.B., Rathore F.A., Clegg D., Rasker J.J. Pulmonary rehabilitation in COVID-19 patients: a scoping review of current practice and its application during the pandemic. Turk. J. Phys. Med. Rehabil. 2020;66(4):480–494. DOI: 10.5606/tftrd.2020.6889</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Spruit M.A., Singh S.J., Garvey C. et al. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am. J. Respir. Crit. Care Med. 2013; 188(8): e13–e64. DOI: 10.1164/rccm.201309-1634ST</mixed-citation><mixed-citation xml:lang="en">Spruit M.A., Singh S.J., Garvey C. et al. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am. J. Respir. Crit. Care Med. 2013; 188(8): e13–e64. DOI: 10.1164/rccm.201309-1634ST</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Yang X., Yu Y., Xu J. et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir. Med. 2020;8(5):475–481. DOI: 10.1016/S2213-2600(20)30079-5</mixed-citation><mixed-citation xml:lang="en">Yang X., Yu Y., Xu J. et al. Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study. Lancet Respir. Med. 2020;8(5):475–481. DOI: 10.1016/S2213-2600(20)30079-5</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Levy J., Léotard A., Lawrence C. et.al. A model for a ventilator-weaning and early rehabilitation unit to deal with post-ICU impairments following severe COVID-19. Ann. Phys. Rehabil. Med. 2020;63(4):376–378. DOI: 10.1016/j.rehab.2020.04.002</mixed-citation><mixed-citation xml:lang="en">Levy J., Léotard A., Lawrence C. et.al. A model for a ventilator-weaning and early rehabilitation unit to deal with post-ICU impairments following severe COVID-19. Ann. Phys. Rehabil. Med. 2020;63(4):376–378. DOI: 10.1016/j.rehab.2020.04.002</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Simpson R., Robinson L. Rehabilitation following critical illness in people with COVID-19 infection. Am. J. Phys. Med. Rehabil. 2020; 10.1097/PHM.0000000000001443. DOI: 10.1097/PHM.0000000000001443</mixed-citation><mixed-citation xml:lang="en">Simpson R., Robinson L. Rehabilitation following critical illness in people with COVID-19 infection. Am. J. Phys. Med. Rehabil. 2020; 10.1097/PHM.0000000000001443. DOI: 10.1097/PHM.0000000000001443</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Thomas P., Baldwin C., Bissett B., Boden I. et. al. Physiotherapy management for COVID-19 in the acute hospital setting: clinical practice recommendations. J. Physiother. 2020;66(2):73–82. DOI: 10.1016/j.jphys.2020.03.011</mixed-citation><mixed-citation xml:lang="en">Thomas P., Baldwin C., Bissett B., Boden I. et. al. Physiotherapy management for COVID-19 in the acute hospital setting: clinical practice recommendations. J. Physiother. 2020;66(2):73–82. DOI: 10.1016/j.jphys.2020.03.011</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Wang T.J., Chau B., Lui M. et al. Physical medicine and rehabilitation and pulmonary rehabilitation for COVID-19. Am. J. Phys. Med. Rehabil. 2020;99(9):769–774. DOI: 10.1097/PHM.0000000000001505</mixed-citation><mixed-citation xml:lang="en">Wang T.J., Chau B., Lui M. et al. Physical medicine and rehabilitation and pulmonary rehabilitation for COVID-19. Am. J. Phys. Med. Rehabil. 2020;99(9):769–774. DOI: 10.1097/PHM.0000000000001505</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Yang F., Liu N., Hu J.Y. et al. Pulmonary rehabilitation guidelines in the principle of 4S for patients infected with 2019 novel coronavirus (2019-nCoV). Zhonghua Jie He He Hu Xi Za Zhi. 2020.12;43(3):180–182. DOI: 10.3760/cma.j.issn.1001-0939.2020.03.007</mixed-citation><mixed-citation xml:lang="en">Yang F., Liu N., Hu J.Y. et al. Pulmonary rehabilitation guidelines in the principle of 4S for patients infected with 2019 novel coronavirus (2019-nCoV). Zhonghua Jie He He Hu Xi Za Zhi. 2020.12;43(3):180–182. DOI: 10.3760/cma.j.issn.1001-0939.2020.03.007</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Fink J.B. Positioning versus postural drainage. Respir. Care. 2002;47(7):769–777.</mixed-citation><mixed-citation xml:lang="en">Fink J.B. Positioning versus postural drainage. Respir. Care. 2002;47(7):769–777.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Cullen D.L., Rodak B. Clinical utility of measures of breathlessness. Respir. Care. 2002;47(9):986–993.</mixed-citation><mixed-citation xml:lang="en">Cullen D.L., Rodak B. Clinical utility of measures of breathlessness. Respir. Care. 2002;47(9):986–993.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Gautam A.P., Arena R., Dixit S., Borghi-Silva A. Pulmonary rehabilitation in COVID-19 pandemic era: The need for a revised approach. Respirology. 2020;25(12):1320–1322. DOI: 10.1111/resp.13946</mixed-citation><mixed-citation xml:lang="en">Gautam A.P., Arena R., Dixit S., Borghi-Silva A. Pulmonary rehabilitation in COVID-19 pandemic era: The need for a revised approach. Respirology. 2020;25(12):1320–1322. DOI: 10.1111/resp.13946</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Parry S.M., Knight L.D., Connolly B. et. al. Factors influencing physical activity and rehabilitation in survivors of critical illness: a systematic review of quantitative and qualitative studies. Intensive Care Med. 2017;43(4):531–542. DOI: 10.1007/s00134-017-4685-4</mixed-citation><mixed-citation xml:lang="en">Parry S.M., Knight L.D., Connolly B. et. al. Factors influencing physical activity and rehabilitation in survivors of critical illness: a systematic review of quantitative and qualitative studies. Intensive Care Med. 2017;43(4):531–542. DOI: 10.1007/s00134-017-4685-4</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Временные методические рекомендации «Медицинская реабилитация при новой коронавирусной инфекции (COVID-19). Версия 2 (31.07.2020)». 151 с. URL: https://static-0.minzdrav.gov.ru/system/attachments/attaches/000/051/187/original/31072020_Reab_COVID-19_v1.pdf</mixed-citation><mixed-citation xml:lang="en">Temporary guidelines «Medical rehabilitation for a new coronavirus infection (COVID-19). Version 2 (31.07.2020)». 151 p. (in Russian). URL: https://static-0.minzdrav.gov.ru/system/attachments/attaches/000/051/187/original/31072020_Reab_COVID-19_v1.pdf</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Zhao H.M., Xie Y.X., Wang C et al. Recommendations for respiratory rehabilitation in adults with coronavirus disease 2019. Chin. Med. J. (Engl.). 2020;133(13):1595–1602. DOI: 10.1097/CM9.0000000000000848</mixed-citation><mixed-citation xml:lang="en">Zhao H.M., Xie Y.X., Wang C et al. Recommendations for respiratory rehabilitation in adults with coronavirus disease 2019. Chin. Med. J. (Engl.). 2020;133(13):1595–1602. DOI: 10.1097/CM9.0000000000000848</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Grigoletto I., Cavalheri V., Lima F.F., Ramos E.M.C. Recovery after COVID-19: The potential role of pulmonary rehabilitation. Braz. J. Phys. Ther. 2020;24(6):463–464. DOI: 10.1016/j.bjpt.2020.07.002</mixed-citation><mixed-citation xml:lang="en">Grigoletto I., Cavalheri V., Lima F.F., Ramos E.M.C. Recovery after COVID-19: The potential role of pulmonary rehabilitation. Braz. J. Phys. Ther. 2020;24(6):463–464. DOI: 10.1016/j.bjpt.2020.07.002</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Barazzoni R., Bischoff S.C., Breda J. et al. ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection. Clin. Nutr. 2020;39(6):1631–1638. DOI: 10.1016/j.clnu.2020.03.022</mixed-citation><mixed-citation xml:lang="en">Barazzoni R., Bischoff S.C., Breda J. et al. ESPEN expert statements and practical guidance for nutritional management of individuals with SARS-CoV-2 infection. Clin. Nutr. 2020;39(6):1631–1638. DOI: 10.1016/j.clnu.2020.03.022</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Carfì A., Bernabei R., Landi F., Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute COVID-19. JAMA. 2020;324(6):603–605. DOI: 10.1001/jama.2020.12603</mixed-citation><mixed-citation xml:lang="en">Carfì A., Bernabei R., Landi F., Gemelli Against COVID-19 Post-Acute Care Study Group. Persistent symptoms in patients after acute COVID-19. JAMA. 2020;324(6):603–605. DOI: 10.1001/jama.2020.12603</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Khan F., Amatya B. Medical rehabilitation in pandemics: towards a new perspective. J. Rehabil. Med. 2020;52(4):jrm00043. DOI: 10.2340/16501977-2676</mixed-citation><mixed-citation xml:lang="en">Khan F., Amatya B. Medical rehabilitation in pandemics: towards a new perspective. J. Rehabil. Med. 2020;52(4):jrm00043. DOI: 10.2340/16501977-2676</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Ambrosino N., Fracchia C. The role of tele-medicine in patients with respiratory diseases. Expert Rev. Respir. Med. 2017;11(11):893–900. DOI: 10.1080/17476348.2017.1383898</mixed-citation><mixed-citation xml:lang="en">Ambrosino N., Fracchia C. The role of tele-medicine in patients with respiratory diseases. Expert Rev. Respir. Med. 2017;11(11):893–900. DOI: 10.1080/17476348.2017.1383898</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Yang L.L., Yang T. Pulmonary rehabilitation for patients with coronavirus disease 2019 (COVID-19). Chronic Dis. Transl. Med. 2020;6(2):79–86. DOI: 10.1016/j.cdtm.2020.05.002</mixed-citation><mixed-citation xml:lang="en">Yang L.L., Yang T. Pulmonary rehabilitation for patients with coronavirus disease 2019 (COVID-19). Chronic Dis. Transl. Med. 2020;6(2):79–86. DOI: 10.1016/j.cdtm.2020.05.002</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Liu K., Zhang W., Yang Y. et al. Respiratory rehabilitation in elderly patients with COVID-19: a randomized controlled study. Complement Ther. Clin. Pract. 2020;39:101166. DOI: 10.1016/j.ctcp.2020.101166</mixed-citation><mixed-citation xml:lang="en">Liu K., Zhang W., Yang Y. et al. Respiratory rehabilitation in elderly patients with COVID-19: a randomized controlled study. Complement Ther. Clin. Pract. 2020;39:101166. DOI: 10.1016/j.ctcp.2020.101166</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Donner C.F., Raskin J., ZuWallack R. et al. Incorporating telemedicine into the integrated care of the COPD patient a summary of an interdisciplinary workshop held in Stresa, Italy, 7-8 September 2017. Respir. Med. 2018;143:91–102. DOI: 10.1016/j.rmed.2018.09.003</mixed-citation><mixed-citation xml:lang="en">Donner C.F., Raskin J., ZuWallack R. et al. Incorporating telemedicine into the integrated care of the COPD patient a summary of an interdisciplinary workshop held in Stresa, Italy, 7-8 September 2017. Respir. Med. 2018;143:91–102. DOI: 10.1016/j.rmed.2018.09.003</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Bartlo P., Bauer N. Pulmonary rehabilitation post-acute care for COVID-19 (PACER). URL: https://youtu.be/XjY_7O3Qpd8 (data of access: 11.05.2020).</mixed-citation><mixed-citation xml:lang="en">Bartlo P., Bauer N. Pulmonary rehabilitation post-acute care for COVID-19 (PACER). URL: https://youtu.be/XjY_7O3Qpd8 (data of access: 11.05.2020).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
