<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">docru</journal-id><journal-title-group><journal-title xml:lang="ru">Доктор.Ру</journal-title><trans-title-group xml:lang="en"><trans-title>Title</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-2378</issn><issn pub-type="epub">2713-2994</issn><publisher><publisher-name>ООО "ГК "РУСМЕДИКАЛ"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31550/1727-2378-2023-22-2-26-31</article-id><article-id custom-type="elpub" pub-id-type="custom">docru-223</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КАРДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CARDIOLOGY</subject></subj-group></article-categories><title-group><article-title>Проблемы диагностики синдрома постуральной ортостатической тахикардии. Клинические примеры</article-title><trans-title-group xml:lang="en"><trans-title>Problems with the Diagnostics of Postural Orthostatic Tachycardia Syndrome. Case Studies</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9242-2838</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гвоздева</surname><given-names>Ю. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Gvozdeva</surname><given-names>Yu. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гвоздева Юлия Романовна — студент лечебного факультета ИПО ФГБОУ ВО КрасГМУ им. проф. В.Ф. Войно-Ясенецкого Минздрава России.</p><p>660022, Красноярск, ул. Партизана Железняка, д. 1</p></bio><bio xml:lang="en"><p>1 Partizan Zheleznyak Str., Krasnoyarsk, 660022</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1294-3116</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кантимирова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kantimirova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кантимирова Елена Анатольевна — к. м. н., доцент кафедры медицинской генетики и клинической нейрофизиологии ИПО ФГБОУ ВО КрасГМУ им. проф. В.Ф. Войно-Ясенецкого Минздрава России.</p><p>660022, Красноярск, ул. Партизана Железняка, д. 1</p></bio><bio xml:lang="en"><p>1 Partizan Zheleznyak Str., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">kantilea@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4639-6365</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дмитренко</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dmitrenko</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дмитренко Диана Викторовна — д. м. н., доцент, заведующая кафедрой медицинской генетики и клинической нейрофизиологии ИПО ФГБОУ ВО КрасГМУ им. проф. В.Ф. Войно-Ясенецкого Минздрава России.</p><p>660022, Красноярск, ул. Партизана Железняка, д. 1</p></bio><bio xml:lang="en"><p>1 Partizan Zheleznyak Str., Krasnoyarsk, 660022</p></bio><email xlink:type="simple">mart2802@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого» Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Professor V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>18</day><month>02</month><year>2025</year></pub-date><volume>22</volume><issue>2</issue><issue-title>ТЕРАПИЯ</issue-title><fpage>26</fpage><lpage>31</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гвоздева Ю.Р., Кантимирова Е.А., Дмитренко Д.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Гвоздева Ю.Р., Кантимирова Е.А., Дмитренко Д.В.</copyright-holder><copyright-holder xml:lang="en">Gvozdeva Y.R., Kantimirova E.A., Dmitrenko D.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://docru.elpub.ru/jour/article/view/223">https://docru.elpub.ru/jour/article/view/223</self-uri><abstract><sec><title>Цель статьи</title><p>Цель статьи: в клинических примерах продемонстрировать сложности диагностики синдрома постуральной ортостатической тахикардии.</p></sec><sec><title>Основные положения</title><p>Основные положения. Спектр клинических проявлений синдрома постуральной ортостатической тахикардии различается у разных пациентов и может иметь сходный клинический фенотип с большим числом неврологических и соматических заболеваний.</p></sec><sec><title>Заключение</title><p>Заключение. Представленные нами клинические случаи демонстрируют значимость диагностических мероприятий в проведении дифференциальной диагностики синдрома с другими видами нарушения сознания. Активный тест стоя, который можно легко выполнить, может немедленно дать диагностическую подсказку, если он подтверждается историей характерной хронической ортостатической непереносимости, постуральным учащением сердечного ритма и разнообразной панорамой сопутствующих жалоб.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective of the Review</title><p>Objective of the Review: To demonstrate the complexity in diagnosing postural orthostatic tachycardia syndrome.</p></sec><sec><title>Key Points</title><p>Key Points. Clinical manifestations of postural orthostatic tachycardia syndrome vary and can have a clinical phenotype that is similar to a number of neurological and somatic conditions.</p></sec><sec><title>Conclusion</title><p>Conclusion. The case studies presented demonstrate the significance of diagnostic manoeuvres in differentiating this syndrome from other types of impairment of consciousness. An active test in standing position which is easy to conduct can be a diagnostic prompt, if it is verified with a history of typical chronic orthostatic intolerability, postural heart acceleration, and a variety of accompanying complaints.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>синдром постуральной ортостатической тахикардии</kwd><kwd>потери сознания</kwd><kwd>диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>postural orthostatic tachycardia syndrome</kwd><kwd>loss of consciousness</kwd><kwd>diagnostics</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Sheldon R.S., Grubb II B.P., Olshansky B. et al. Heart rhythm society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope. Heart Rhythm. 2015;12(6):41–63. DOI: 10.1016/j.hrthm.2015.03.029</mixed-citation><mixed-citation xml:lang="en">Sheldon R.S., Grubb II B.P., Olshansky B. et al. Heart rhythm society expert consensus statement on the diagnosis and treatment of postural tachycardia syndrome, inappropriate sinus tachycardia, and vasovagal syncope. Heart Rhythm. 2015;12(6):41–63. DOI: 10.1016/j.hrthm.2015.03.029</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Arnold A.C., Ng J., Raj S.R. Postural tachycardia syndrome — diagnosis, physiology, and prognosis. Auton. Neurosci. 2018;215:3–11. DOI: 10.1016/j.autneu.2018.02.005</mixed-citation><mixed-citation xml:lang="en">Arnold A.C., Ng J., Raj S.R. Postural tachycardia syndrome — diagnosis, physiology, and prognosis. Auton. Neurosci. 2018;215:3–11. DOI: 10.1016/j.autneu.2018.02.005</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">AbdelRazek M., Low Ph., Rocca W., Singer W. Epidemiology of postural tachycardia syndrome (S18.005). Neurology. 2019;92(15Suppl.):S18.005</mixed-citation><mixed-citation xml:lang="en">AbdelRazek M., Low Ph., Rocca W., Singer W. Epidemiology of postural tachycardia syndrome (S18.005). Neurology. 2019;92(15Suppl.):S18.005</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Shibao C., Arzubiaga C., Roberts L.J. et al. Hyperadrenergic postural tachycardia syndrome in mast cell activation disorders. Hypertension. 2005;45(3):385–390. DOI: 10.1161/01.HYP.0000158259.68614.40</mixed-citation><mixed-citation xml:lang="en">Shibao C., Arzubiaga C., Roberts L.J. et al. Hyperadrenergic postural tachycardia syndrome in mast cell activation disorders. Hypertension. 2005;45(3):385–390. DOI: 10.1161/01.HYP.0000158259.68614.40</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Haensch C.A., Lerch H., Schlemmer H. et al. Cardiac neurotransmission imaging with 123I-meta-iodobenzylguanidine in postural tachycardia syndrome. J. Neurol. Neurosurg. Psychiatry. 2010;81(3):339–343. DOI: 10.1136/jnnp.2008.168484</mixed-citation><mixed-citation xml:lang="en">Haensch C.A., Lerch H., Schlemmer H. et al. Cardiac neurotransmission imaging with 123I-meta-iodobenzylguanidine in postural tachycardia syndrome. J. Neurol. Neurosurg. Psychiatry. 2010;81(3):339–343. DOI: 10.1136/jnnp.2008.168484</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Johansson M., Stahberg M., Runold M. et al. Long-haul post-COVID-19 symptoms presenting as a variant of postural orthostatic tachycardia syndrome: the swedish experience. Am. Coll. Cardiol. Case Rep. 2021;3(4):573–580. DOI: 10.1016/j.jaccas.2021.01.009</mixed-citation><mixed-citation xml:lang="en">Johansson M., Stahberg M., Runold M. et al. Long-haul post-COVID-19 symptoms presenting as a variant of postural orthostatic tachycardia syndrome: the swedish experience. Am. Coll. Cardiol. Case Rep. 2021;3(4):573–580. DOI: 10.1016/j.jaccas.2021.01.009</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Miglis M.G., Prieto T., Shaik R. et al. A case report of postural tachycardia syndrome after COVID-19. Clin. Auton. Res. 2020;30(5):449–451. DOI: 10.1007/s10286-020-00727-9</mixed-citation><mixed-citation xml:lang="en">Miglis M.G., Prieto T., Shaik R. et al. A case report of postural tachycardia syndrome after COVID-19. Clin. Auton. Res. 2020;30(5):449–451. DOI: 10.1007/s10286-020-00727-9</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Трисветова Е.Л. Синдром постуральной ортостатической тахикардии как проявление постковидного синдрома. Рациональная фармакотерапия в кардиологии. 2022;18(2):200–208. DOI: 10.20996/1819-6446-2022-04-11</mixed-citation><mixed-citation xml:lang="en">Trisvetova E.L. Postural orthostatic tachycardia syndrome as a manifestation of post-COVID-19 syndrome. Rational pharmacotherapy in cardiology. 2022;18(2):200–208. (in Russian). DOI: 10.20996/1819-6446-2022-04-11</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Chelimsky G., Chelimsky T. The gastrointestinal symptoms present in patients with postural tachycardia syndrome: A review of the literature and overview of treatment. Autonomic Neurosci. 2018;215:70–77. DOI: 10.1016/j.autneu.2018.09.003</mixed-citation><mixed-citation xml:lang="en">Chelimsky G., Chelimsky T. The gastrointestinal symptoms present in patients with postural tachycardia syndrome: A review of the literature and overview of treatment. Autonomic Neurosci. 2018;215:70–77. DOI: 10.1016/j.autneu.2018.09.003</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Raj S.R. The postural tachycardia syndrome (POTS): pathophysiology, diagnosis &amp; management. Ind. Pacing Electrophysiol. J. 2006;6(2):84–99.</mixed-citation><mixed-citation xml:lang="en">Raj S.R. The postural tachycardia syndrome (POTS): pathophysiology, diagnosis &amp; management. Ind. Pacing Electrophysiol. J. 2006;6(2):84–99.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Raj V.O., Opie M., Arnold A.C. Cognitive and psychological issues in postural tachycardia syndrome. Auton. Neurosci. 2018;215:45–55. DOI: 10.1016/j.autneu.2018.03.004</mixed-citation><mixed-citation xml:lang="en">Raj V.O., Opie M., Arnold A.C. Cognitive and psychological issues in postural tachycardia syndrome. Auton. Neurosci. 2018;215:45–55. DOI: 10.1016/j.autneu.2018.03.004</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Strassheim V., Welford J., Ballantine R., Newton J.L. Managing fatigue in postural tachycardia syndrome (POTS): The Newcastle approach. Auton. Neurosci. 2018;215:56–61. DOI: 10.1016/j.autneu.2018.02.003</mixed-citation><mixed-citation xml:lang="en">Strassheim V., Welford J., Ballantine R., Newton J.L. Managing fatigue in postural tachycardia syndrome (POTS): The Newcastle approach. Auton. Neurosci. 2018;215:56–61. DOI: 10.1016/j.autneu.2018.02.003</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Fu Q., Levine B.D. Exercise and non-pharmacological treatment of pots. Auton. Neurosci. 2018;215:20–27. DOI: 10.1016/j.autneu.2018.07.001</mixed-citation><mixed-citation xml:lang="en">Fu Q., Levine B.D. Exercise and non-pharmacological treatment of pots. Auton. Neurosci. 2018;215:20–27. DOI: 10.1016/j.autneu.2018.07.001</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Shen W.K., Sheldon R.S., Benditt D.G. et al. 2017 acc/aha/hrs guideline for the evaluation and management of patients with syncope: executive summary: a report of the American College of Cardiology. American Heart Association Task Force on clinical practice guidelines and the Heart Rhythm Society. Circulation. 2017;36(5):620–663. DOI: 10.1161/CIR.0000000000000498</mixed-citation><mixed-citation xml:lang="en">Shen W.K., Sheldon R.S., Benditt D.G. et al. 2017 acc/aha/hrs guideline for the evaluation and management of patients with syncope: executive summary: a report of the American College of Cardiology. American Heart Association Task Force on clinical practice guidelines and the Heart Rhythm Society. Circulation. 2017;36(5):620–663. DOI: 10.1161/CIR.0000000000000498</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Kavin L., Nuttall M., Low D.A. et al. A profile of patients with postural tachycardia syndrome and their experience of healthcare in the UK. Br. J. Cardiol. 2016;23:1–6. DOI: 10.5837/bjc.2016.010</mixed-citation><mixed-citation xml:lang="en">Kavin L., Nuttall M., Low D.A. et al. A profile of patients with postural tachycardia syndrome and their experience of healthcare in the UK. Br. J. Cardiol. 2016;23:1–6. DOI: 10.5837/bjc.2016.010</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Насырова Р.Ф., Сивакова Н.А., Липатова Л.В. и др. Биологические маркеры эффективности и безопасности противоэпилептических препаратов: фармакогенетика и фармакокинетика. Сибирское медицинское обозрение. 2017;(1):17–25. DOI: 10.20333/2500136-2017-1-17-25</mixed-citation><mixed-citation xml:lang="en">Nasyrova R.F., Sivakova N.A., Lipatova L.V. et al. Biological markers of the antiepileptic drugs efficacy and safety: pharmacogenetics and pharmacokinetics. Siberian Medical Review. 2017;(1):17–25. (in Russian). DOI: 10.20333/2500136-2017-1-17-25</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Dmitrenko D.V., Strotskaya I.G., Artyukhov I.P. et al. Arrhythmogenic covulsive syncope in neurological practice: a case report. Int. J. Biomed. 2018;8(1):65–68. DOI: 10.21103/Article8(1)_CR1</mixed-citation><mixed-citation xml:lang="en">Dmitrenko D.V., Strotskaya I.G., Artyukhov I.P. et al. Arrhythmogenic covulsive syncope in neurological practice: a case report. Int. J. Biomed. 2018;8(1):65–68. DOI: 10.21103/Article8(1)_CR1</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Vernino S., Bourne K.M., Stiles L.E. et al. Postural orthostatic tachycardia syndrome (POTS): state of the science and clinical care from a 2019. National Institutes of Health expert consensus meeting — part 1. Auton. Neurosci. 2021;235. DOI: 10.1016/j.autneu.2021.102828</mixed-citation><mixed-citation xml:lang="en">Vernino S., Bourne K.M., Stiles L.E. et al. Postural orthostatic tachycardia syndrome (POTS): state of the science and clinical care from a 2019. National Institutes of Health expert consensus meeting — part 1. Auton. Neurosci. 2021;235. DOI: 10.1016/j.autneu.2021.102828</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Fedorowski A. Postural orthostatic tachycardia syndrome: clinical presentation, aetiology and management (review). J. Intern. Med. 2019;285(4):352–366. DOI: 10.1111/joim.12852</mixed-citation><mixed-citation xml:lang="en">Fedorowski A. Postural orthostatic tachycardia syndrome: clinical presentation, aetiology and management (review). J. Intern. Med. 2019;285(4):352–366. DOI: 10.1111/joim.12852</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Boris J.R. Postural orthostatic tachycardia syndrome in children and adolescents. Auton. Neurosci. 2018;215:97–101. DOI: 10.1016/j.autneu.2018.05.004</mixed-citation><mixed-citation xml:lang="en">Boris J.R. Postural orthostatic tachycardia syndrome in children and adolescents. Auton. Neurosci. 2018;215:97–101. DOI: 10.1016/j.autneu.2018.05.004</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Boris J.R., Huang J., Bernadzikowski T. Orthostatic heart rate does not predict symptomatic burden in pediatric patients with chronic orthostatic intolerance. Clin. Auton. Res. 2020;30(1):19–28.; DOI: 10.1007/s10286-019-00622-y</mixed-citation><mixed-citation xml:lang="en">Boris J.R., Huang J., Bernadzikowski T. Orthostatic heart rate does not predict symptomatic burden in pediatric patients with chronic orthostatic intolerance. Clin. Auton. Res. 2020;30(1):19–28.; DOI: 10.1007/s10286-019-00622-y</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Chelimsky G., Chelimsky T. The gastrointestinal symptoms present in patients with postural tachycardia syndrome: a review of the literature and overview of treatment. Auton. Neurosci. 2018;215:70–77. DOI: 10.1016/j.autneu.2018.09.003</mixed-citation><mixed-citation xml:lang="en">Chelimsky G., Chelimsky T. The gastrointestinal symptoms present in patients with postural tachycardia syndrome: a review of the literature and overview of treatment. Auton. Neurosci. 2018;215:70–77. DOI: 10.1016/j.autneu.2018.09.003</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Boris J.R., Bernadzikowski T. Demographics of a large paediatric Postural Orthostatic Tachycardia Syndrome Program. Cardiol. Young. 2018;28(5):668–674. DOI: 10.1017/S1047951117002888</mixed-citation><mixed-citation xml:lang="en">Boris J.R., Bernadzikowski T. Demographics of a large paediatric Postural Orthostatic Tachycardia Syndrome Program. Cardiol. Young. 2018;28(5):668–674. DOI: 10.1017/S1047951117002888</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Freeman R., Wieling W., Axelrod F.B. et al. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin. Auton. Res. 2011;21(2):69–72. DOI: 10.1007/s10286-011-0119-5</mixed-citation><mixed-citation xml:lang="en">Freeman R., Wieling W., Axelrod F.B. et al. Consensus statement on the definition of orthostatic hypotension, neurally mediated syncope and the postural tachycardia syndrome. Clin. Auton. Res. 2011;21(2):69–72. DOI: 10.1007/s10286-011-0119-5</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Brignole M., Moya A., de Lange F.J. et al. 2018 ESC Guidelines for the diagnosis and management of syncope. Eur. Heart J. 2018;39(21):1883–1948. DOI: 10.1093/eurheartj/ehy037</mixed-citation><mixed-citation xml:lang="en">Brignole M., Moya A., de Lange F.J. et al. 2018 ESC Guidelines for the diagnosis and management of syncope. Eur. Heart J. 2018;39(21):1883–1948. DOI: 10.1093/eurheartj/ehy037</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
