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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">docru</journal-id><journal-title-group><journal-title xml:lang="ru">Доктор.Ру</journal-title><trans-title-group xml:lang="en"><trans-title>Title</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1727-2378</issn><issn pub-type="epub">2713-2994</issn><publisher><publisher-name>ООО "ГК "РУСМЕДИКАЛ"</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.31550/1727-2378-2024-23-8-9-14</article-id><article-id custom-type="elpub" pub-id-type="custom">docru-216</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ПЕРЕДОВАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>LEAD ARTICLE</subject></subj-group></article-categories><title-group><article-title>Метаболическое здоровье при ожирении:  перспективы и вызовы</article-title><trans-title-group xml:lang="en"><trans-title>Metabolic Health and Obesity: Prospects and Challenges</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7936-7619</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аметов</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ametov</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аметов Александр Сергеевич — д. м. н., профессор, заведующий кафедрой эндокринологии, заведующий сетевой кафедрой ЮНЕСКО по теме «Биоэтика сахарного диабета как глобальная проблема»; ведущий научный сотрудник отделения эндокринологии</p><p>г. Москва</p></bio><bio xml:lang="en"><p>Moscow</p></bio><email xlink:type="simple">alexander.ametov@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России; ГБУЗ «Московский многопрофильный научно-клинический центр имени С.П. Боткина Департамента здравоохранения города &#13;
Москвы»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Medical Academy of Continuous Professional Education; Botkin Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>18</day><month>02</month><year>2025</year></pub-date><volume>23</volume><issue>8</issue><issue-title>КАРДИОМЕТАБОЛИЧЕСКАЯ МЕДИЦИНА</issue-title><fpage>9</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аметов А.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Аметов А.С.</copyright-holder><copyright-holder xml:lang="en">Ametov A.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://docru.elpub.ru/jour/article/view/216">https://docru.elpub.ru/jour/article/view/216</self-uri><abstract><p>Метаболическое здоровье является ключевым фактором в профилактике и лечении большинства хронических заболеваний. Сохранение метаболического здоровья — важнейшее направление современной медицины, и оно требует комплексного подхода, включающего в себя выявление факторов риска, модификацию образа жизни, поиск новых возможностей коррекции факторов риска и взаимодействие разных специалистов во благо пациентов.</p></abstract><trans-abstract xml:lang="en"><p>Metabolic health is a key factor in prevention and management of the majority of chronic conditions. Metabolic health prevention is a priority area of the modern healthcare, and it requires a comprehensive approach, which includes identification of the risk factors, lifestyle modification, search for new possible ways to correct the risk factors, and cooperation of various specialists for the benefit of the patient.</p></trans-abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Schulze M.B., Stefan N. Metabolically healthy obesity: from epidemiology and mechanisms to clinical implications. Nat. Rev. Endocrinol. 2024;20(11):633–46. doi: 10.1038/s41574-02401008-5</mixed-citation><mixed-citation xml:lang="en">Schulze M.B., Stefan N. Metabolically healthy obesity: from epidemiology and mechanisms to clinical implications. Nat. Rev. Endocrinol. 2024;20(11):633–46. doi: 10.1038/s41574-02401008-5</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Wani K., Kumar B., Saba I., Sabico S. The metabolically healthy obese phenotype: the atypical normal or disorder in progress? J. Biol. Regulators Homeostatic Agents. 2023;37(6):2863–76. DOI: 10.23812/j.biol.regul.homeost.agents.20233706.284</mixed-citation><mixed-citation xml:lang="en">Wani K., Kumar B., Saba I., Sabico S. The metabolically healthy obese phenotype: the atypical normal or disorder in progress? J. Biol. Regulators Homeostatic Agents. 2023;37(6):2863–76. DOI: 10.23812/j.biol.regul.homeost.agents.20233706.284</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Johnson C., Drummer Iv C., Shan H., Shao Y. et al. A novel subset of CD95+ pro-inflammatory macrophages overcome miR155 deficiency and may serve as a switch from metabolically healthy obesity to metabolically unhealthy obesity. Front. Immunol. 2021;11:619951. DOI: 10.3389/fimmu.2020.619951</mixed-citation><mixed-citation xml:lang="en">Johnson C., Drummer Iv C., Shan H., Shao Y. et al. A novel subset of CD95+ pro-inflammatory macrophages overcome miR155 deficiency and may serve as a switch from metabolically healthy obesity to metabolically unhealthy obesity. Front. Immunol. 2021;11:619951. DOI: 10.3389/fimmu.2020.619951</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
