docruДоктор.РуTitle1727-23782713-2994ООО "ГК "РУСМЕДИКАЛ"10.31550/1727-2378-2023-22-7-13-17docru-213Research ArticleГАСТРОЭНТЕРОЛОГИЯGASTROENTEROLOGYМембраны жировых глобул молока: значение для адаптации жирового компонента молочных смесейMilk Fat Globule Membranes: Significance for Adaptation of the Fat Components of Formulashttps://orcid.org/0000-0003-4200-4598ЗахароваИ. Н.ZakharovaI. N.

Захарова Ирина Николаевна  — д. м. н., профессор, заведующая кафедрой педиатрии имени академика Г.Н. Сперанского 

 125993, г. Москва, ул. Баррикадная, д. 2/1, стр. 1 

2/1 Barrikadnaya Str., build. 1, Moscow,  125993

zakharova-rmapo@yandex.ruhttps://orcid.org/0000-0003-0668-7336ДмитриеваЮ. А.DmitrievaYu. A.

Дмитриева Юлия Андреевна  — к. м. н., врач-педиатр, детский гастроэнтеролог, доцент кафедры педиатрии имени академика Г.Н. Сперанского

125993,  г. Москва, ул. Баррикадная, д. 2/1, стр.1

2/1 Barrikadnaya Str., build. 1, Moscow,  125993

jadmitrieva@mail.ruФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Министерства здравоохранения Российской ФедерацииРоссияRussian Medical Academy of Continuous Professional EducationRussian Federation202318022025227ПЕДИАТРИЯ1317Copyright © Захарова И.Н., Дмитриева Ю.А., 20252025Захарова И.Н., Дмитриева Ю.А.Zakharova I.N., Dmitrieva Y.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://docru.elpub.ru/jour/article/view/213Цель обзора

Цель обзора. На основании данных литературы проанализировать клиническое значение мембран жировых глобул молока в питании новорожденных и детей раннего возраста.

Основные положения

Основные положения. «Золотым стандартом» вскармливания ребенка первого года было и остается грудное молоко. Составы современных молочных смесей разрабатываются на основе новых данных о компонентах женского молока, оказывающих важнейшее программирующее влияние на растущий организм ребенка. Особое внимание ученые обращают в настоящее время на оптимизацию жирового компонента смесей за счет введения мембран жировых глобул молока — уникальной структуры, окружающей глицериновое ядро и включающей в себя комплексные липиды в форме фосфолипидов, ганглиозидов и холестерина.

Заключение

Заключение. Научные исследования продемонстрировали важнейшую роль минорных липидов в процессе постнатального формирования центральной нервной системы и зрительного анализатора, становления иммунной системы и регуляции метаболических процессов. Убедительно доказаны хорошая переносимость смеси, содержащей мембраны жировых глобул молока, а также ее положительные эффекты в отношении профилактики инфекционных заболеваний и состояния липидного обмена.

Aim

Aim. Based on literature data, to analyze the clinical significance of the milk fat globule membrane in the nutrition of newborns and young children.

Key points

Key points. Breast milk has been and remains the “gold standard” for feeding a child of the first year. The composition of modern formulas is based on the new information on the breast milk components, which have the most important programming impact on the growing child body. Currently, scientists pay special attention to the optimisation of the fat component of formulas with the introduction of milk fat globule membranes — a unique structure surrounding glycerine nucleus and comprising complex lipids in the form of phospholipids, gangliosides and cholesterol.

Conclusion

Conclusion. The scientific studies demonstrated the critical role of “minor” lipids in the process of postnatal formation of the central nervous system and visual analyzer, the formation of the immune system and the regulation of metabolic processes. It is now reliably known that formulas with milk fat globule membranes are well-tolerated and have favourable effect on the prevention of infectious diseases and lipid exchange status.

молочная смесьдлинноцепочечные полиненасыщенные жирные кислотыклеточные мембранымембрана жировых глобул молокаmilk formulalong chain polyunsaturated fatty acidscell membranesmilk fat globule membraneСтатья подготовлена при финансовой поддержке компании ООО «ХИРОУ РУС» (бренд Semper), однако это не оказало влияния на мнение авторовThe article has been funded by the financial support from Hero Rus LLC (Semper brand); however, it has not influenced the authors' own opinions.ReferencesLucas A. Long-term programming effects of early nutrition — implications for the preterm infant. J. Perinatol. 2005;25(suppl.2):S2–6. DOI: 10.1038/sj.jp.7211308Lucas A. Long-term programming effects of early nutrition — implications for the preterm infant. J. Perinatol. 2005;25(suppl.2):S2–6. DOI: 10.1038/sj.jp.7211308Захарова И.Н., Дмитриева Ю.А., Гордеева Е.А. Совершенствование детских молочных смесей — на пути приближения к женскому молоку. 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The authors declare that there are no conflicts of interest present.